20 articles
New research reveals how tumors sabotage T cell metabolism by transferring dysfunctional mitochondria, offering fresh immunotherapy targets.
A Nature study reveals neurons physically transfer mitochondria to breast cancer cells via tunneling nanotubes, boosting metastatic potential.
Comprehensive review reveals how mitochondrial dysfunction fuels cancer progression and identifies promising therapeutic opportunities.
New review reveals how cancer biology has fundamentally transformed our understanding of mitochondrial plasticity and its implications beyond oncology.
A new Science paper reveals that mitochondrial fitness in dendritic cells controls antitumor immunity — and can be targeted to boost immunotherapy.
Novel treatment triggers ferroptosis in cancer cells while activating immune responses that further enhance cancer cell death.
A landmark Cell study reveals cells transfer cytoplasmic DNA fragments to neighbors via nanotubes, stably reshaping recipient genomes.
New review reveals how targeting mitochondria in cancer cells could overcome immunotherapy resistance and enhance anti-tumor responses.
Novel nanoplatform delivers copper and iron ions to trigger both ferroptosis and cuproptosis in cancer cells.
Review reveals how cardiolipin dysregulation drives glioblastoma survival and identifies potential therapeutic vulnerabilities.
New nanotechnology selectively destroys cancer cell mitochondria, making tumors more vulnerable to T cell attacks across multiple cancer types.
New research shows how activating PKM2 enzyme enhances CD8 T cell function and improves anti-PD1 cancer therapy effectiveness.
A newly discovered hepatic micropeptide suppresses liver cancer progression by jamming a key mitochondrial RNA processing complex.
A comprehensive review reveals how iron-driven cell death can be exploited to treat ATC, one of the most lethal human cancers.
Engineered green tea compound nanoparticles activate cellular powerhouses to suppress tumor growth and improve immune response against melanoma.
Redirecting glucose metabolism during T cell expansion dramatically improves cancer immunotherapy effectiveness.
Novel nanoparticle combines protein degrader with light therapy to reprogram cancer metabolism and eliminate breast tumors.
New study reveals how immune cells in tumors deliver protective proteins that block a promising cancer treatment approach.
New research reveals how liver immune cells trigger bile duct cancer through chronic mitochondrial dysfunction and oxidative stress.
Leukemic stem cells produce their own ketone bodies to block ferroptosis, revealing a metabolic weak point that could be targeted therapeutically.
