20 articles
Microglia package healthy mitochondria into vesicles and deliver them to astrocytes, sharply reducing cognitive decline in tau-pathology mice.
Scientists used red blood cells to transport healthy mitochondria into diseased brain cells, showing promise for Parkinson's treatment.
Simple compound successfully treats life-threatening COQ2 deficiency in newborn, offering hope for rare mitochondrial disorders.
Dr. Martin Picard reveals how mitochondria translate mindset, stress, and behaviors into cellular energy that determines aging rate.
Scientists developed mitoDREADD-Gs, a novel tool that restores cognitive function by enhancing mitochondrial activity in mouse models of dementia.
A new tool that boosts mitochondrial activity in neurons restored memory in dementia mice, suggesting energy failure drives Alzheimer's symptoms.
A new mechanism links mitochondrial DNA trafficking through lysosomes to gasdermin-driven pyroptosis, with Parkinson's disease genes playing a key role.
New research reveals how electroacupuncture helps stroke recovery by promoting transfer of healthy mitochondria from support cells to damaged neurons.
Large study finds genetic background doesn't explain mitochondrial damage in neurodegenerative disease, pointing to complex causes.
Nicotinamide riboside prevents moyamoya-like brain vessel blockages by fixing cellular energy production in smooth muscle cells.
A new review reveals that disrupted mito-nuclear signaling may precede amyloid and tau pathology, opening fresh therapeutic targets for Alzheimer's.
Duke researchers restored healthy mitochondria to damaged nerve cells, cutting pain-related behaviors by 50% in mice with nerve pain.
New research reveals mitochondrial dysfunction as the starting point of Alzheimer's disease, offering early intervention targets.
New research reveals how stroke disrupts mitochondria and endoplasmic reticulum, offering targets for neuroprotection.
New review reveals how protein clumps and cellular powerhouses work together to drive neurodegeneration in Parkinson's disease.
Dr. Glen Jeffery reveals how long-wavelength light passes through skin and clothing to enhance cellular energy production.
Cryo-EM reveals VPS13A and scramblase XK work together to ferry lipids across organelle contact sites, unlocking a fundamental cell biology mystery.
Excessive vigorous exercise triggers a muscle-derived factor that acts as a mitochondrial imposter, impairing cognitive function.
Researchers combined ultrasound with gene therapy to treat Leigh syndrome, significantly extending survival in mouse models.
New research reveals how TDP-43 protein causes energy failure in motor neurons, pointing to potential metabolic therapies for ALS.
