20 articles
Scientists review breakthrough methods for transferring healthy mitochondria into damaged cells to restore cellular energy and combat aging.
Packaging mitochondria in erythrocyte-derived membranes dramatically improves delivery efficiency, pushing this experimental therapy closer to clinical reality.
A comprehensive review of pathophysiology, genetics, and emerging therapies for mitochondrial myopathies, spotlighting elamipretide and gene therapy.
Scientists use red blood cells to transport healthy mitochondria into diseased brain cells, showing promise for treating Parkinson's.
A sweeping review maps every known strategy for delivering therapies directly to mitochondria, from lifestyle habits to nanocarriers and gene editing.
Revolutionary delivery system uses microscopic gel capsules to transport healthy mitochondria to damaged heart cells after heart attack.
NO-primed extracellular vesicles transfer functional mitochondria to damaged kidney cells, restoring energy production and reducing injury.
Dynamic 3D culture systems enhance stem cells' ability to transfer healing mitochondria via tunneling nanotubes, accelerating wound repair.
Novel nanoparticle therapy converts inflammatory macrophages into healing cells that deliver healthy mitochondria to damaged spinal discs.
Scientists discover muscle cells bypass normal nuclear pores to export oversized RNA transcripts via a newly identified budding pathway.
New technique combines your own cells with light therapy to supercharge mitochondria for dramatic skin regeneration and wound healing.
A Phase 1/2 trial of NFS-02 gene therapy for LHON-associated vision loss was terminated before completion, raising questions about mitochondrial gene therapy.
Engineered iron nanoparticles restore bone health by transferring healthy mitochondria from immune cells to aging bone marrow stem cells.
Mitochondria-targeted antioxidant polymer shows superior protection against liver transplant injury compared to standard treatments.
Embryonic brain precursor cells grafted into adult rat striatum successfully integrate and reduce motor deficits in a Parkinson's disease model.
Novel nanogel therapy targets mitochondrial ROS to break the inflammation-hypoxia cycle in periodontitis, showing strong preclinical results.
Researchers erased imprinting marks in mouse sperm using dCas9-TET1, then traced how methylation partially recovered — fingering H3K9me3 as the key mediator.
Breakthrough technology allows precise activation of genes in living animals using electromagnetic fields, opening new therapeutic possibilities.
A rigorous mechanistic deep-dive into the molecular logic of partial reprogramming — from chromatin dynamics and epigenetic clock reversal to in vivo delivery strategies, oncogenic risks, and the path to clinical translation.
Japanese researchers develop minimally invasive method to transform T cells into glutamatergic neurons using just 5 factors.
