Test Longevity Interventions In Your Own Cells Before You Try Them
Mike Lustgarten explores using cellular testing to screen longevity interventions personally before committing to them.
84 articles
Mike Lustgarten explores using cellular testing to screen longevity interventions personally before committing to them.
A new minimal model from physicists suggests aging is governed by just 3 variables β and most anti-aging drugs only address the first level.
Independent testing exposes widespread quality failures in NAD+ precursor supplements, with actionable guidance on which brands actually deliver.
A new review maps the molecular mechanisms behind liver aging and evaluates dietary, drug, and gene-editing interventions to slow decline.
A comprehensive review reveals how aging and disturbed blood flow reprogram endothelial cell metabolism, fueling atherosclerosis through glycolytic, lipid, and mitochondrial dysregulation.
A landmark review synthesizes 12 hallmarks of aging, emerging gerotherapeutics, and a new three-tier clinical care model to shift medicine from disease treatment to aging prevention.
A Danish case-control trial uses gold-standard metabolic testing to uncover how mtDNA mutations impair muscle glucose uptake and drive insulin resistance.
Elevated CD38 in monocytes depletes NAD+ and fuels fibrosis in myeloproliferative neoplasms β blocking CD38 or boosting NAD+ may reverse disease.
A 2026 review of 32 human studies identifies which supplements genuinely support muscle, brain, metabolism, and immunity as we age.
A new review identifies protein, NADβΊ precursors, antioxidants, and probiotics as top evidence-backed supplements for aging adults.
Restoring NAD+ levels in elderly patients' T cells reverses age-related dysfunction, offering a new 'Metabolic-Immunotherapy' approach for cancer treatment.
A landmark review reveals how declining NAD+ levels and disrupted circadian clocks form a vicious cycle driving dementia progression.