20 articles
A multi-biomarker study finds pwMS show accelerated thymic involution, senescent T cell expansion, and neuroinflammation linked to aging.
Go beyond inflammaging basics to understand how aging reshapes immune cell populations, triggers the SASP, and locks the body into a state of chronic low-grade inflammation at the molecular level.
New research reveals how our antibody responses against harmful bacteria mature and strengthen through repeated exposure over time.
A mechanistic deep-dive into cutting-edge anti-inflammaging interventions — from senolytic pharmacology and precision cytokine targeting to partial reprogramming strategies that aim to restore youthful immune homeostasis.
Discover how persistent low-grade inflammation drives the aging process and learn strategies to combat this silent threat to longevity.
New research reveals E. coli dominates and suppresses S. aureus in dual-species implant biofilms, with major implications for treating polymicrobial joint infections.
Go beyond the basics to explore how complement pathways, regulatory failures, and senescent cells interact to drive the chronic inflammation that accelerates aging at the molecular level.
New research reveals how beneficial bacteria help newborn skin develop proper immune responses that protect against chronic inflammation.
New research reveals B cells in brain membranes play crucial roles in neural protection, aging, and neurodegenerative diseases.
RA patients with interstitial lung disease show accelerated cellular aging markers — shorter telomeres and fewer mitochondrial DNA copies than RA patients without lung involvement.
Senescent T cells fuel psoriasis, eczema, and rosacea through toxic secretions. New therapies may finally break the cycle.
Scientists discover how protective immune cells in brain membranes lose their strength during Alzheimer's progression.
Stanford researchers used modified immune proteins to enhance neurogenesis and cognitive function in aged mouse brains.
New research reveals how tissue fibroblasts orchestrate age-related inflammation, creating exhausted T cells that increase vulnerability to disease.
Master the molecular architecture of complement dysregulation in aging — from regulatory protein biochemistry to cutting-edge therapeutic targets — and understand how precision interventions can restore balance without dismantling immunity.
Scientists reveal how macrophages use mitochondria to clear dead cells while controlling immune responses, offering insights for healthier aging.
Discover how a hidden arm of your immune system called the complement system quietly drives the chronic inflammation linked to aging — and what you can do about it.
New research reveals how RNA-binding proteins orchestrate immune responses, offering insights into preventing chronic inflammation.
Mice lacking the PERP apoptosis gene develop faulty thymic immune screening, accumulating self-reactive T-cells that trigger arthritis as they age.
New study reveals specific immune and microbiome signatures that could predict depression in lupus patients with 85% accuracy.
