How Aging's Inflammatory Clock Fuels Colorectal Cancer Risk
A major review reveals how inflammaging and immunosenescence synergistically drive colorectal cancer in older adults, reshaping the tumor microenvironment.
20 articles
A major review reveals how inflammaging and immunosenescence synergistically drive colorectal cancer in older adults, reshaping the tumor microenvironment.
A sweeping 2025 review maps how gut, tumor, and systemic microbiomes promote or suppress cancer across every major tumor type.
New research reveals young and elderly cervical cancer patients have completely different molecular signatures requiring age-specific treatments.
Specific mutational signatures accumulate linearly with age in normal tissues, offering a new window into why cancer risk rises exponentially as we get older.
Large study reveals cancer survivors have higher biological age than cancer-free individuals, with strongest mortality predictions from epigenetic clocks.
New research reveals how a common gut bacterium reprograms immune cells to accelerate colorectal cancer progression.
Machine learning models achieve 88-97% accuracy in detecting gastric cancer risk through microbiome analysis, opening new paths for early detection.
Researchers propose guidelines to study how microbes within tumors influence cancer progression and treatment responses.
Scientists discover how two microbes team up to accelerate colon cancer, but L-arginine may disrupt their deadly partnership.
Fusobacterium nucleatum has shifted from suspected bystander to confirmed cancer driver โ here's what the science reveals.
Mouse study reveals the FXR bile acid receptor links gut microbes to arterial plaque in sleep apnea, hinting at new preventive targets.
Study identifies senescent EGR1+ B cells that sabotage immunotherapy in esophageal cancer, with fisetin showing promise as a therapeutic enhancer.
Cambridge scientists engineer a nanoprobe that detects therapy-induced senescence non-invasively through a simple urine colorimetric test.
Researchers developed rat and mouse models mimicking early and middle stages of oral submucous fibrosis using bleomycin injections.
A cancer patient on nivolumab developed Eikenella corrodens bacteremia after CNS infection, revealing how immune checkpoint therapy may enable dangerous microbial dissemination.
Specific gut bacteria enhance anti-PD-1 cancer treatment by converting immune cells into powerful tumor fighters.
Specific bacterial metabolic pathways in the gut determine whether cancer immunotherapy works by controlling immune responses.
New research reveals colorectal cancer has distinct microbial communities that could improve diagnosis and personalized treatment approaches.
Specific gut microbes produce compounds that reprogram fat cells to enhance immune responses against cancer.
New research reveals senescent cells have both harmful and protective roles, pushing anti-aging science toward targeted removal strategies.