Aging Gut Loses Its Defenses and Lets Harmful Bacteria Take Over
New mouse research reveals how intestinal aging creates a feedback loop of inflammation, barrier breakdown, and microbiome decline.
20 articles
New mouse research reveals how intestinal aging creates a feedback loop of inflammation, barrier breakdown, and microbiome decline.
New research proposes the immune system actively controls gut microbiome diversity, and that aging-related immune decline drives dysbiosis.
resbiotic partners with Tiny Health to offer shotgun metagenomic gut testing at home, linking microbiome data to aging and chronic symptoms.
A Lactobacillus strain found in centenarians reduced lung fibrosis scores by 30% and collagen by 40% in aging mice via the gut-lung axis.
A 20,000-person study finds IgG glycan patterns track biological aging, predict mortality, and shift toward youth with interventions.
A 12-week clinical trial found older adults taking probiotics with antidepressants had greater reductions in depression and anxiety than placebo.
Scientists find phosphatidylcholine loss fragments mitochondrial networks with age β and supplementing it may help reverse the damage.
Massive cellular atlas shows aging starts earlier than expected and happens in sync across 21 organs, opening doors to targeted therapies.
Rockefeller scientists mapped epigenomic aging across 7M cells in 21 tissues, uncovering coordinated, program-like shifts that may unlock new therapies.
New research links chronic low-grade inflammation to faster epigenetic aging, measured across four validated biological clocks.
Hidden root infections trigger chronic inflammation that disrupts insulin function β and treating them may improve metabolic health.
Glycans β sugar molecules on proteins β shift with stress, diet, and lifestyle, and may predict disease a decade before symptoms appear.
From NAD+ restoring aged muscle to meal timing accelerating aging, April's research roundup delivers actionable longevity insights.
A 20,000-person study validates IgG glycans as aging biomarkers, with therapeutic plasma exchange reducing glycan age by 0.4 years per month.
New research reveals sugar pushes skin cells into senescence and slows repair, linking diet directly to accelerated skin and systemic aging.
Research reveals when you eat your first and last meals may influence how fast your body ages at the cellular level.
A new commentary argues public health leaders can no longer treat geroscience as optional β demographic math has made it urgent policy.
Stanford researchers found ribosome stalling in aging brain cells triggers faulty proteins and toxic clumps linked to Alzheimer's disease.
A class of modified amino acids found in dog blood may unlock new ways to measure and track biological aging across species.
Cells actively remodel their protein factories as we age, potentially triggering diseaseβbut this process could be targeted to slow aging.