Results for "Partial Epigenetic Reprogramming" in Alzheimer's

20 articles

Repurposed Anti-Nausea Drug TEP Tested for Clearing Alzheimer's Brain Plaques
Brain Health

Repurposed Anti-Nausea Drug TEP Tested for Clearing Alzheimer's Brain Plaques

A Phase 2 trial investigates whether thiethylperazine, a decades-old antiemetic, can flush toxic amyloid beta from the brains of early AD patients.

Clinical Trial
Jun 12, 2026 0
Integrative Learning Program Boosts Function and Well-Being in Older Adults With Dementia
Brain Health

Integrative Learning Program Boosts Function and Well-Being in Older Adults With Dementia

A structured neuroplasticity-based program improved functional performance and emotional well-being in community-dwelling older adults with dementia.

Clinical Trial
Jun 5, 2026 0
Johns Hopkins Study Reveals How Psilocybin Changes Brain Emotion Processing
Brain Health

Johns Hopkins Study Reveals How Psilocybin Changes Brain Emotion Processing

Small pilot study examined psilocybin's effects on brain circuits and emotion processing in healthy adults to understand abuse potential.

Clinical Trial
Mar 29, 2026 0
Precision Medicine Shows Promise for Reversing Early Dementia and Memory Loss
Brain Health

Precision Medicine Shows Promise for Reversing Early Dementia and Memory Loss

Personalized treatment approach targeting multiple causes of cognitive decline outperformed standard care in 9-month trial.

Clinical Trial
Mar 28, 2026 2
Hip Hop Music Program Fights Alzheimer's Stigma in Kids and Spanish-Speaking Families
Brain Health

Hip Hop Music Program Fights Alzheimer's Stigma in Kids and Spanish-Speaking Families

A Columbia University trial tests whether a hip hop-based dementia education program builds lasting literacy and reduces stigma in children and families.

Clinical Trial
Jun 11, 2026 0
Digital Brain Training Program Shows Promise for Healthy Aging in Older Adults
Brain Health

Digital Brain Training Program Shows Promise for Healthy Aging in Older Adults

German researchers test whether digital environmental enrichment can boost mental and physical wellbeing in seniors through telehealth.

Clinical Trial
Mar 28, 2026 1
Gut Bacteria Transplants Show Promise for Treating Parkinson's Disease Symptoms
Brain Health

Gut Bacteria Transplants Show Promise for Treating Parkinson's Disease Symptoms

Clinical trial explores whether resetting gut microbiome through fecal transplants can slow Parkinson's progression and reduce symptoms.

Clinical Trial
Mar 28, 2026 1
Rapastinel Shows Lower Abuse Potential Than Ketamine in Phase 1 Trial
Brain Health

Rapastinel Shows Lower Abuse Potential Than Ketamine in Phase 1 Trial

A completed Phase 1 trial compared the abuse liability of rapastinel versus ketamine in recreational polydrug users, with implications for safer depression treatment.

Clinical Trial
Jun 5, 2026 0
First Human Trial of Oral D-Peptide Drug Targeting Alzheimer's Toxic Oligomers Completed
Brain Health

First Human Trial of Oral D-Peptide Drug Targeting Alzheimer's Toxic Oligomers Completed

Contraloid acetate, an oral all-D-peptide designed to disassemble toxic amyloid-beta oligomers, completed its first-in-human safety trial in 40 healthy volunteers.

Clinical Trial
Jun 12, 2026 0
Exercise Program Shows Promise for Veterans with Dementia in Clinical Trial
Brain Health

Exercise Program Shows Promise for Veterans with Dementia in Clinical Trial

Novel movement program combining Eastern and Western exercises may help maintain independence and cognitive function in dementia patients.

Clinical Trial
Mar 28, 2026 0
Mapping the Infant Brain from 3 to 12 Months Reveals How Experience Shapes Development
Brain Health

Mapping the Infant Brain from 3 to 12 Months Reveals How Experience Shapes Development

A completed longitudinal study tracks brain structure, function, and behavior in healthy infants across the first year of life.

Clinical Trial
Jun 30, 2026 0
Rural Community Program Targets Alzheimer's Risk Through Lifestyle Interventions
Brain Health

Rural Community Program Targets Alzheimer's Risk Through Lifestyle Interventions

Small pilot study tests multicomponent behavioral program to reduce cognitive decline risk in underserved rural populations.

Clinical Trial
Mar 28, 2026 1
Your Genes May Determine How Much Exercise Benefits Your Brain
Brain Health

Your Genes May Determine How Much Exercise Benefits Your Brain

Small study reveals BDNF genetic variant could influence exercise's cognitive and cardiovascular benefits in healthy men.

Clinical Trial
Mar 28, 2026 2
Magnetic Brain Stimulation Boosts Memory and Thinking Skills in Older Adults
Brain Health

Magnetic Brain Stimulation Boosts Memory and Thinking Skills in Older Adults

Duke University study tests whether targeted brain stimulation can reverse age-related cognitive decline and improve working memory.

Clinical Trial
Mar 28, 2026 0
New Drug Shows Promise in Preventing Alzheimer's Amyloid Buildup in Young Adults
Brain Health

New Drug Shows Promise in Preventing Alzheimer's Amyloid Buildup in Young Adults

NGP 555 targets toxic brain protein production in healthy volunteers, offering potential early intervention for Alzheimer's prevention.

Clinical Trial
Mar 28, 2026 0
Retired Cholesterol Drug Shows Promise for Alzheimer's Prevention in Small Trial
Brain Health

Retired Cholesterol Drug Shows Promise for Alzheimer's Prevention in Small Trial

Probucol, a discontinued cholesterol medication, may boost brain-protective proteins in older adults at risk for dementia.

Clinical Trial
Mar 29, 2026 0
Light Therapy Shows Promise for Sleep and Memory in Alzheimer's and Cognitive Decline
Brain Health

Light Therapy Shows Promise for Sleep and Memory in Alzheimer's and Cognitive Decline

Clinical trial explores how targeted light treatment could restore circadian rhythms and improve brain function in mild cognitive impairment.

Clinical Trial
Mar 28, 2026 2
Drugs That Boost Brain Waste Clearance During Sleep Show Promise Against Alzheimer's
Brain Health

Drugs That Boost Brain Waste Clearance During Sleep Show Promise Against Alzheimer's

A Phase 1/2 trial tests whether dexmedetomidine can enhance the brain's glymphatic system to clear amyloid and tau during sleep.

Clinical Trial
May 16, 2026 0
New Device Aims to Measure Brain's Waste-Clearing System During Sleep
Brain Health

New Device Aims to Measure Brain's Waste-Clearing System During Sleep

Applied Cognition tests a wearable device that tracks glymphatic function overnight, comparing it to MRI, EEG, and blood biomarkers.

Clinical Trial
May 16, 2026 0
Memory Boot Camp Shows Promise for Reversing Mild Cognitive Decline in Older Adults
Brain Health

Memory Boot Camp Shows Promise for Reversing Mild Cognitive Decline in Older Adults

12-week intensive cognitive training program tested in 76 adults with early memory problems to assess brain function improvements.

Clinical Trial
Mar 28, 2026 0
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