20 articles
Researchers identify N4BP2, the enzyme behind chromothripsis - a genetic catastrophe that helps one in four cancers rapidly evolve and resist treatment.
Researchers discovered how to restore tumor-killing power in worn-out immune cells by switching off just two genes.
A small molecule called UNI418 shuts down cancer cells' DNA repair machinery, making drug-resistant tumors vulnerable to treatment again.
A new DNA-based treatment blocks the PCSK9 protein, cutting LDL cholesterol by nearly 50% while avoiding common statin side effects.
When the DNA-repair gene EXO1 is overproduced, it damages DNA instead of fixing it—exposing a hidden vulnerability in multiple cancers.
New research reveals senescent cells have both harmful and protective roles, pushing anti-aging science toward targeted removal strategies.
Experimental PCAI compounds blocked over 90% of pancreatic cancer cell migration and triggered self-destruction by hyperactivating tumor growth pathways.
MYC protein doesn't just fuel tumor growth — it also repairs DNA damage from chemotherapy, revealing a key resistance mechanism.
A UCLA study found that aggressive small cell cancers lacking the RB gene depend on protein E2F3 to survive — blocking it stopped tumor growth in lab models.
New research reveals how tumors reprogram neutrophils to produce CCL3, turning immune defenders into cancer allies.
Northwestern researchers dramatically boosted cancer vaccine effectiveness by simply repositioning one protein fragment on their nanovaccine.
Revolutionary CRISPR technique bypasses lab manufacturing by programming immune cells to fight cancer directly in the body.
USC researchers unlocked a scalable supply of engineered immune-cell precursors that fight tumors and may revolutionize cancer immunotherapy.
New compound AP503 activates GPR133 receptor to rebuild bone density in mice, offering hope for millions with osteoporosis.
Scientists found drugs that kill senescent 'zombie cells' by blocking their key survival protein, shrinking tumors in mice.
Scientists discover nerve fibers create a self-sustaining loop that accelerates pancreatic cancer development before tumors even form.
Disabling the NFIL3 protein prevents CAR T cell exhaustion, boosting tumor-fighting power in animal models of hard-to-treat cancers.
New AI tool automatically identifies cells with chromosomal defects that may lead to cancer, helping scientists study how cancer begins.
New research reveals colorectal cancer has distinct microbial communities that could improve diagnosis and personalized treatment approaches.
McGill scientists boosted NK cell cancer-killing power using reversible drug treatment, targeting leukemia, glioblastoma, and triple-negative breast cancer.
