Metabolic Health
Pyruvate Directly Rewrites Your Epigenome When Blood Sugar Spikes
A new PTM called lysine pyruvylation links glycolytic activity directly to gene regulation, with SIRT3 acting as the eraser.
Research Paper
Jul 5, 2026 0
Results for "Partial Epigenetic Reprogramming" in Diabetes
20 articles
Metabolic Health
Maternal Obesity Programs Muscle Weakness in Children Through Genetic Switches
New research reveals how obesity during pregnancy triggers genetic changes that cause lasting muscle dysfunction in offspring.
Research Paper
Mar 29, 2026 3
Metabolic Health
Glucose Triggers Fat Cell Formation Through Epigenetic Chromatin Remodeling
New research reveals how glucose metabolism directly controls fat tissue expansion through a novel epigenetic pathway involving JMJD1A.
Research Paper
Apr 3, 2026 0
Metabolic Health
Magnetic Field Pulses Boost Embryonic Muscle Development in Just 10 Minutes a Week
Brief weekly PEMF exposures increased quail embryo weight by ~20%, body length by ~15%, and upregulated key oxidative muscle genes.
Research Paper
Apr 24, 2026 0
Metabolic Health
AI-Powered Nutrigenetics Slashes BMI and Reverses Biological Aging in Morbid Obesity
A 6-month AI-driven personalized diet intervention cut BMI by 33% and reduced biological age by 8 years in morbidly obese patients.
Research Paper
May 21, 2026 0
Metabolic Health
DunedinPACE Epigenetic Clock Predicts Metabolic Syndrome 7 Years Before Onset
New study shows DunedinPACE aging biomarker can predict who will develop metabolic syndrome years in advance, outperforming other epigenetic clocks.
Research Paper
Apr 2, 2026 0
Metabolic Health
DNA Methylation Clocks Predict Diabetes Risk Better Than Expected
Second-generation epigenetic clocks show strong associations with metabolic syndrome and type 2 diabetes risk prediction.
Research Paper
Mar 27, 2026 20
Metabolic Health
Single Molecule Activates Five Receptors to Target Obesity and Metabolic Disease
A novel conjugate merges GLP-1/GIP incretin signaling with pan-PPAR activation in one molecule, potentially revolutionizing metabolic therapy.
Research Paper
May 9, 2026 0
Metabolic Health
Metabolic Syndrome Accelerates Biological Aging by Over a Year
Large NHANES study reveals metabolic syndrome causes measurable acceleration in epigenetic aging clocks, offering new targets for intervention.
Research Paper
Apr 3, 2026 0
Metabolic Health
Melatonin Reverses Metabolic Damage in IVF Children by Fixing Liver Enzymes
New research shows melatonin supplementation during IVF can prevent obesity and glucose problems in offspring by restoring liver function.
Research Paper
Apr 9, 2026 0
Metabolic Health
New Peptide Analog Burns Fat Continuously Without Reducing Appetite
Prolactin-releasing peptide analog promotes sustained fat burning for weight loss, offering new approach beyond appetite suppression.
Research Paper
Mar 28, 2026 1
Metabolic Health
Scientists Discover Key Protein That Drives Liver Scarring and Potential Treatment Target
New research reveals how SREBP2 protein triggers liver fibrosis through metabolic changes, offering hope for treating liver disease.
Research Paper
Mar 28, 2026 1
Metabolic Health
New Local Immune Engineering Approach Could Transform Diabetes Islet Transplants
Researchers shift from systemic B-cell targeting to localized immune control, potentially improving transplant success rates.
Research Paper
Mar 28, 2026 0
Metabolic Health
New Immune Engineering Approach Shows Promise for Diabetes Islet Transplants
Researchers explore targeted immune strategies to improve pancreatic islet transplant success rates for diabetes treatment.
Research Paper
Mar 28, 2026 0
Metabolic Health
Bacteria That Eat Industrial Surfactants Reveal Key Biodegradation Genes
Transcriptomic analysis of Pseudomonas nitroreducens TX1 identifies 241 differentially expressed genes during surfactant degradation.
Research Paper
Apr 23, 2026 0
Metabolic Health
Brain Gene FTO Drives Obesity by Hijacking Appetite Neuron Cargo Delivery
FTO demethylase in AgRP neurons alters Kif1a splicing to boost neuropeptide release, promoting weight gain in mice.
Research Paper
Apr 19, 2026 0
Metabolic Health
Recurrent Low Blood Sugar Does Not Rewire Brain Glucose Transport in Type 1 Diabetes
A rigorous MRI-based study finds that repeated hypoglycemia episodes leave brain glucose transport kinetics unchanged, challenging a leading hypothesis.
Research Paper
May 14, 2026 0
Metabolic Health
Mitochondrial Complex I Reverses Metabolic Syndrome in Circadian-Disrupted Mice
Restoring mitochondrial complex I function in fat cells prevents obesity-related metabolic dysfunction, even without weight loss.
Research Paper
Mar 29, 2026 1
Metabolic Health
PEMF Therapy Boosts Mitochondrial ATP Synthesis Without Affecting Uncoupled Respiration
New research reveals pulsed electromagnetic field therapy selectively enhances ATP-linked mitochondrial respiration, pointing to a specific cellular energy mechanism.
Research Paper
Apr 22, 2026 0
Metabolic Health
Two Gene Variants Combine to Trigger Earlier Diabetes Onset in Rare Family Study
A Japanese family case reveals how inherited HNF1A and ABCC8 mutations act additively to accelerate early-onset diabetes beyond either variant alone.
Research Paper
Apr 23, 2026 0
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