Genetic Testing Could Revolutionize Personalized Dementia Prevention
New precision medicine approach combines genetic risk factors with environmental exposures to predict and prevent dementia.
20 articles
New precision medicine approach combines genetic risk factors with environmental exposures to predict and prevent dementia.
Researchers combined ultrasound with gene therapy to treat Leigh syndrome, significantly extending survival in mouse models.
Study of 2,366 women shows biological aging markers predict future increases in tau, amyloid, and neuroinflammation proteins linked to dementia.
Stanford-led framework defines the five core components of medical digital twins and maps how AI plus mechanistic modeling can create living patient simulations.
DNA methylation biomarkers from a simple blood test may track cognitive aging and neurological disease risk with unprecedented precision.
A NEJM perspective piece explores the hidden meaning and emotional depth found in everyday clinical encounters.
Three-decade study tracks MS prevalence, lifestyle factors, and mortality patterns in England, revealing important health trends.
New research reveals how the longevity protein Klotho may protect against Alzheimer's disease, with Mediterranean diet potentially boosting levels.
Researchers develop 98% accurate plasma protein panel that detects ALS disease process years before clinical onset.
A 38-year Finnish cohort study finds higher lifelong physical activity protects information processing and working memory into midlife.
New research reveals combined treatments targeting multiple brain pathways outperform traditional single-drug strategies for Alzheimer's disease.
Online portal reveals public preferences for dementia treatments, with safety concerns outweighing efficacy in drug selection decisions.
OSK gene therapy targeting engram neurons restored memory to youthful levels in aged mice and Alzheimer's models, reversing senescence hallmarks.
Researchers discover a phospholipid derivative that protects brain cells by calming overactive immune cells in dementia-prone mice.
New research explores how combining multiple supplements could offer breakthrough treatments for brain diseases like Alzheimer's and Parkinson's.
New research reveals statins could reduce dementia risk by 85% in genetically susceptible individuals, offering personalized prevention.
Breakthrough antisense therapy demonstrates sustained benefits for rare genetic form of ALS in extended clinical trial.
New molecular mapping technique identifies individuals uniquely and predicts cognitive decline more accurately than standard brain scans.
Antibody therapies show promise for preventing Alzheimer's in cognitively healthy people with disease biomarkers.
Recent breakthrough drugs targeting amyloid plaques slow cognitive decline, but combination therapies may unlock better outcomes.