Scientists Restore Memory in Mice by Blocking a Single Alzheimer's Protein
Blocking the protein PTP1B boosted memory and cleared brain plaque in mice, with potential links to diabetes and obesity treatment.
20 articles
Blocking the protein PTP1B boosted memory and cleared brain plaque in mice, with potential links to diabetes and obesity treatment.
New mouse research finds the trendy D+Q senolytic combo severely damages myelin, raising red flags for longevity self-experimenters.
Researchers identified the gene that transports queuosine, a micronutrient crucial for brain health and cancer defense, solving a decades-old mystery.
Raising Sox9 levels in aging astrocytes reduced amyloid plaque buildup and protected memory in mouse models with existing Alzheimer's symptoms.
New compounds targeting the cPLA2 enzyme may reduce Alzheimer's-linked brain inflammation, especially in high-risk APOE4 gene carriers.
Researchers discover TMEM175, a cellular safeguard that prevents toxic buildup linked to Parkinson's when it malfunctions.
Researchers created modified psilocin that maintains antidepressant effects while dramatically reducing psychedelic side effects in mice.
A molecule called OLE restores microglia's protective function, reducing amyloid plaques and improving memory in animal models.
UCLA scientists discover why some neurons resist Alzheimer's better than others, revealing a natural protein cleanup system that could lead to new treatments.
Declining Menin in the hypothalamus drives inflammation and aging. Restoring it reversed decline; D-serine amino acid improved cognition in mice.
Stanford researchers found ribosome stalling in aging brain cells triggers faulty proteins and toxic clumps linked to Alzheimer's disease.
Researchers turned ordinary brain cells into plaque-clearing machines, reducing Alzheimer's amyloid by half in mice with one treatment.
UC Davis scientists created novel brain-healing molecules that activate key serotonin receptors tied to neuroplasticity โ without triggering hallucinations.
Researchers discover toxic protein pair that kills brain cells in Alzheimer's and develop compound to block it in mice.
Arginine supplements reduced toxic amyloid buildup, brain inflammation, and behavioral decline in fly and mouse Alzheimer's models.
Astrocytes, once thought passive, actively control fear memories in the brain, opening new paths for anxiety disorder treatments.
Baylor scientists find tubulin redirects rogue brain proteins away from toxic aggregates, pointing to a novel neurodegenerative disease strategy.
A 12-week clinical trial found older adults taking probiotics with antidepressants had greater reductions in depression and anxiety than placebo.
Scientists discover tanycytes help clear toxic tau from the brain. When damaged, these cells may allow Alzheimer's progression.
Major study identifies three existing drugs that could be repurposed to fight Alzheimer's disease, offering faster path to treatment.