Reprogrammed Apoptotic Platelets Stop Bleeding Faster Than Clinical Standards
Scientists engineer high-PS procoagulant platelets that outperform thrombin and commercial hemostatic agents, even in antiplatelet-treated patients.
20 articles
Scientists engineer high-PS procoagulant platelets that outperform thrombin and commercial hemostatic agents, even in antiplatelet-treated patients.
Explore the molecular mechanisms of cellular senescence and how p16/p21 pathways drive SASP production, plus cutting-edge senolytic drug targets.
A novel anti-swelling hydrogel loaded with dasatinib, quercetin, and nucleus pulposus exosomes clears senescent cells and restores disc integrity in rats and goats.
Tiny particles from stem cells could deliver therapeutic benefits without the risks of traditional cell-based treatments.
Novel iodide-enhanced hydrogel penetrates gum pockets to eliminate harmful bacteria while protecting regenerative stem cells.
Scientists discover how histone methyltransferase Setd8 maintains retinal stem cells, offering insights into developmental biology.
Breakthrough prodrug technology enables oral delivery of allopregnanolone, showing promise for treating anxiety and mood disorders.
Discover exosomes โ the microscopic 'text messages' your cells send to coordinate healing, aging, and repair throughout your body.
New delivery system combines stem cell vesicles with hydrogels to cross blood-brain barrier and treat neurological disorders.
A landmark Cell study reveals p53 actively enables chemical reprogramming to pluripotency, overturning assumptions and boosting regenerative medicine safety.
Revolutionary delivery system uses microscopic gel capsules to transport healthy mitochondria to damaged heart cells after heart attack.
A comprehensive review maps how mesenchymal stem cells and their exosomes combat Alzheimer's, atherosclerosis, osteoporosis, and ovarian failure.
Mitochondria-targeted antioxidant polymer shows superior protection against liver transplant injury compared to standard treatments.
New review reveals how plant-based compounds and stem cell therapies could eliminate aging cells and restore youthful function.
Single injection of protective brain protein via gene therapy fully restored memory formation and dramatically reduced amyloid plaques.
Single-cell sequencing reveals ferroptosis drives pulpitis; thymosin ฮฑ1 restores GPX4, cuts iron overload, and reduces inflammation in cells and rats.
Scientists create 3D brain vessel models that show how NOTCH3 protein drives vascular damage in hereditary stroke disease.
Discover how revolutionary drugs target 'zombie cells' that accumulate with age, potentially reversing aging and extending healthspan.
New research reveals how oxygen deprivation damages brain development in preterm infants and identifies potential therapeutic targets.
A senolytic pairing of dasatinib and quercetin cleared senescent cells at the tendon-bone junction, dramatically improving repair strength in aged rats.