Balanced Fluids vs Saline Show No Difference in Pediatric Septic Shock Outcomes
A landmark 9,000-patient trial finds balanced crystalloids and normal saline perform equally for children in septic shock.
20 articles
A landmark 9,000-patient trial finds balanced crystalloids and normal saline perform equally for children in septic shock.
A 2025 mini-review synthesizes RCTs and meta-analyses showing hypertonic dextrose prolotherapy rivals or beats standard OA injections.
A Phase IIa trial explores whether the HIF-PHI drug daprodustat can safely replace EPO injections in hemodialysis patients with anemia.
FDA approval of the first T1D delay drug nearly doubled islet autoantibody testing, but critical gaps remain in screening healthy children.
Breakthrough study reveals sepiapterin dramatically outperforms existing PKU therapy, offering hope for better metabolic control.
A landmark 500-patient RCT finds sodium bicarbonate offers no benefit over placebo for critically ill adults with metabolic acidosis and shock.
Researchers mapped how anesthetics, nitric oxide, and other drugs alter hemoglobin's grip on oxygen โ with real implications for critical care.
Comprehensive therapy combining Western medicine, traditional Chinese medicine, and lifestyle changes reversed diabetes in majority of patients.
A completed Maastricht trial tests whether targeted protein and exercise can boost muscle protein synthesis before dialysis becomes necessary.
A completed RCT tests whether small-sided football sessions 3x/week improve glucose control and metabolic health in T2DM patients on GLP-1 and SGLT2 drugs.
Low-intensity resistance training with blood flow restriction improved muscle strength and mitochondrial function better than conventional exercise.
Researchers shift from systemic B-cell targeting to localized immune control, potentially improving transplant success rates.
Mediterranean diet, resistance training, and diabetes medication combined to combat sarcopenia and improve metabolic health in older adults.
New research reveals pulsed electromagnetic field therapy selectively enhances ATP-linked mitochondrial respiration, pointing to a specific cellular energy mechanism.
Phase 4 trial tests whether alirocumab can better control non-HDL cholesterol in high-risk type 2 diabetics failing statin therapy.
Small pilot study explored whether platelets could serve as biomarkers for detecting mitochondrial problems linked to diabetes development.
Landmark CKD trials enrolled mostly overweight patients โ new evidence questions whether SGLT2 inhibitors work for lean, non-diabetic individuals.
New research reveals how blood vessel maturity around transplanted insulin-producing cells determines long-term survival.
Major diabetes organizations call for individualized tech approaches to overcome access barriers and reduce health disparities.
Researchers explore targeted immune strategies to improve pancreatic islet transplant success rates for diabetes treatment.