Balanced Fluids vs Saline Show No Difference in Pediatric Septic Shock Outcomes
A landmark 9,000-patient trial finds balanced crystalloids and normal saline perform equally for children in septic shock.
20 articles
A landmark 9,000-patient trial finds balanced crystalloids and normal saline perform equally for children in septic shock.
A 2025 mini-review synthesizes RCTs and meta-analyses showing hypertonic dextrose prolotherapy rivals or beats standard OA injections.
FDA approval of the first T1D delay drug nearly doubled islet autoantibody testing, but critical gaps remain in screening healthy children.
Breakthrough study reveals sepiapterin dramatically outperforms existing PKU therapy, offering hope for better metabolic control.
A landmark 500-patient RCT finds sodium bicarbonate offers no benefit over placebo for critically ill adults with metabolic acidosis and shock.
Comprehensive therapy combining Western medicine, traditional Chinese medicine, and lifestyle changes reversed diabetes in majority of patients.
Low-intensity resistance training with blood flow restriction improved muscle strength and mitochondrial function better than conventional exercise.
Researchers shift from systemic B-cell targeting to localized immune control, potentially improving transplant success rates.
New research reveals pulsed electromagnetic field therapy selectively enhances ATP-linked mitochondrial respiration, pointing to a specific cellular energy mechanism.
Landmark CKD trials enrolled mostly overweight patients โ new evidence questions whether SGLT2 inhibitors work for lean, non-diabetic individuals.
New research reveals how blood vessel maturity around transplanted insulin-producing cells determines long-term survival.
Major diabetes organizations call for individualized tech approaches to overcome access barriers and reduce health disparities.
Researchers explore targeted immune strategies to improve pancreatic islet transplant success rates for diabetes treatment.
New research reveals why Addison's disease patients face higher mortality despite treatment and explores promising therapeutic approaches.
A newly identified protein shields the liver from alcohol injury by bridging mitochondria and fat droplets to enhance fatty acid oxidation.
Combining phentermine-topiramate with digital lifestyle coaching produced 15kg weight loss and reduced heart disease risk over 12 months.
Large-scale study identifies three key blood proteins that predict diabetic retinopathy development with 90% accuracy.
New research reveals pulmonary arterial hypertension involves systemic metabolic dysfunction across multiple organs and immune cells.
Inclisiran safely reduced LDL cholesterol by 28% in adolescents with familial hypercholesterolemia, offering hope for early intervention.
Weekly tirzepatide injections led to up to 22% weight loss in Japanese participants, with 96-100% achieving clinically significant results.