Blood Test Reveals Hidden Cancer Resistance in Prostate Cancer Patients
New study shows circulating tumor cells can predict treatment response and reveal drug resistance patterns.
20 articles
New study shows circulating tumor cells can predict treatment response and reveal drug resistance patterns.
Pfizer's first-in-human trial of PF-07209960, a dual-action immunotherapy fusion protein, was terminated after enrolling 37 patients.
Early PSMA upregulation after enzalutamide predicts shorter survival, but adding Lu-177-PSMA-617 improves outcomes in resistant prostate cancer.
Cambridge scientists engineer a nanoprobe that detects therapy-induced senescence non-invasively through a simple urine colorimetric test.
New study shows combining PET scans with blood DNA tests can identify follicular lymphoma patients at high risk of early relapse.
A first-in-human Phase 1 trial evaluates PF-07257876, a dual-checkpoint bispecific antibody targeting both CD47 and PD-L1, in hard-to-treat cancers.
A phase 2 trial of datopotamab deruxtecan in 100 NSCLC patients reveals a 26% response rate and critical resistance biomarkers.
A prospective cohort study shows combining ctDNA with PSA levels dramatically improves survival prediction in high-volume metastatic prostate cancer patients.
Phase I trial shows NT-I7 safely increases lymphocyte counts and expands cancer-fighting T cells in high-grade glioma patients.
New non-invasive urine protein test accurately predicts which biliary tract cancer patients will respond to immunotherapy treatment.
Phase 1 data from 15 heavily pretreated Japanese myeloma patients confirms talquetamab's safety and efficacy, matching global trial results.
New liquid biopsy analyzes DNA fragments in blood to detect breast cancer early, determine subtypes, and assess lymph node spread.
New ColonTrack model identifies early-stage colorectal cancer with 94% accuracy using three proteins from blood-based extracellular vesicles.
Japanese trial shows dual HER2 blockade with pertuzumab plus trastuzumab improves overall survival even after prior pertuzumab treatment.
New study shows how analyzing fluid from lungs can detect cancer mutations and guide personalized treatment decisions.
Revolutionary liquid biopsy technology uses nanoparticles to detect cancer biomarkers in blood with exceptional precision.
Phase 1/2 umbrella trial matches glioblastoma patients to targeted treatments based on tumor genetics, with temsirolimus showing significant benefit.
New study reveals combination therapy targeting ATR and DNA-PKcs kinases dramatically improves radiation response in ATM-deficient prostate cancers.
Advanced biomarker combinations show 96% accuracy in detecting pancreatic cancer, significantly better than current standard tests.
A 73-patient study finds PD-L1 expression and TERT mutations identify high-grade thyroid cancers most likely to benefit from checkpoint inhibitor therapy.