New PKU Drug Sepiapterin Shows 70% Better Results Than Current Standard Treatment
Breakthrough study reveals sepiapterin dramatically outperforms existing PKU therapy, offering hope for better metabolic control.
20 articles
Breakthrough study reveals sepiapterin dramatically outperforms existing PKU therapy, offering hope for better metabolic control.
Researchers analyzed 2,911 proteins in 50,506 people to create a frailty score that predicts disease risk and biological aging.
50 nm polystyrene nanoplastics accumulate in mouse testes, degrading sperm quality and triggering iron-dependent cell death through a newly identified mitochondrial pathway.
New study shows DunedinPACE aging biomarker can predict who will develop metabolic syndrome years in advance, outperforming other epigenetic clocks.
Large-scale study identifies three key blood proteins that predict diabetic retinopathy development with 90% accuracy.
A newly identified protein shields the liver from alcohol injury by bridging mitochondria and fat droplets to enhance fatty acid oxidation.
Scientists discover how PDAP1 protein reprograms liver cells to burn less fat and make more, driving hepatocellular carcinoma progression.
A Phase IIa trial explores whether the HIF-PHI drug daprodustat can safely replace EPO injections in hemodialysis patients with anemia.
Large study reveals specific blood proteins can identify who will die from heart disease a decade before death occurs.
A 2025 mini-review synthesizes RCTs and meta-analyses showing hypertonic dextrose prolotherapy rivals or beats standard OA injections.
FDA approval of the first T1D delay drug nearly doubled islet autoantibody testing, but critical gaps remain in screening healthy children.
New AI-powered blood test analyzes DNA fragments to catch liver fibrosis and cirrhosis in early, treatable stages before damage becomes irreversible.
Small pilot study explored whether platelets could serve as biomarkers for detecting mitochondrial problems linked to diabetes development.
A steroid hormone activates receptor GPR56 to block ferroptosis, a form of iron-driven cell death linked to liver disease.
Large-scale protein analysis enhanced diabetes risk prediction by 23-29%, offering new tools for early prevention strategies.
Research reveals how the steroid hormone pregnenolone allows cancer cells to evade immune detection and reduces immunotherapy effectiveness.
Scientists discover urinary biomarker that reveals kidney scarring in diabetics years before traditional tests show damage.
Scientists discover how platelet-activating factor drives liver damage in obese women, revealing potential therapeutic targets.
A noninvasive 13-variable score reveals how fast your liver is aging โ and accelerated liver aging raises mortality risk by up to 85%.
A systematic review of 8 studies finds tirzepatide significantly reduces hsCRP and IL-6 across all doses and populations.