Results for "Plasma p-tau217" in Heart Disease

20 articles

Blood Test for P-Tau217 Protein May Predict Dementia Risk Years in Advance
Heart Health

Blood Test for P-Tau217 Protein May Predict Dementia Risk Years in Advance

New biomarker could identify dementia risk decades before symptoms appear, enabling earlier intervention strategies.

Research Paper
Mar 28, 2026 0
Phase 3 Trial Tests Tafamidis for TTR Amyloid Heart Disease
Heart Health

Phase 3 Trial Tests Tafamidis for TTR Amyloid Heart Disease

Pfizer's landmark trial examines whether tafamidis can safely treat transthyretin amyloid cardiomyopathy, a progressive and often fatal heart condition.

Clinical Trial
Jun 13, 2026 0
Lp(a) Genetic Risk Variants Linked to Distinct Coronary Plaque and Thrombus Patterns
Heart Health

Lp(a) Genetic Risk Variants Linked to Distinct Coronary Plaque and Thrombus Patterns

A pathological study ties common Lp(a) risk gene variants to specific coronary thrombosis morphologies in sudden cardiac death victims.

Research Paper
May 18, 2026 0
17-Protein Blood Panel Predicts Heart Failure Risk in Diabetics Far Better Than Standard Tests
Heart Health

17-Protein Blood Panel Predicts Heart Failure Risk in Diabetics Far Better Than Standard Tests

A proteomics screen of 2,920 plasma proteins identifies a 17-protein score that lifts heart failure prediction accuracy to 0.833 C-index in type 2 diabetes patients.

Research Paper
Jun 3, 2026 0
Oxidized Phospholipids on Lp(a) Drive Long-Term Heart Attack Risk Independent of Platelet Effects
Heart Health

Oxidized Phospholipids on Lp(a) Drive Long-Term Heart Attack Risk Independent of Platelet Effects

In 2,040 coronary angiography patients, OxPL-apoB predicted MI-free survival but showed no link to platelet reactivity, implicating Lp(a) as the key mediator.

Research Paper
Jun 4, 2026 0
Blocking Key Protein Delays Obesity and Metabolic Disease in Early Stages
Heart Health

Blocking Key Protein Delays Obesity and Metabolic Disease in Early Stages

New research reveals how eliminating urokinase plasminogen activator can temporarily protect against diet-induced weight gain and metabolic dysfunction.

Research Paper
Mar 29, 2026 1
Thymosin Alpha-1 Tested to Prevent Organ Failure After Emergency Aortic Surgery
Heart Health

Thymosin Alpha-1 Tested to Prevent Organ Failure After Emergency Aortic Surgery

A 330-patient multicenter RCT tests whether thymosin ฮฑ1 can curb immune dysregulation and organ dysfunction after acute type A aortic dissection repair.

Research Paper
Apr 27, 2026 0
TIE2 Receptor Circuit Drives Venous Malformation Growth Beyond PI3K Mutations
Heart Health

TIE2 Receptor Circuit Drives Venous Malformation Growth Beyond PI3K Mutations

A feedforward ANGPT-TIE2 signaling loop amplifies PIK3CA-driven venous malformations, pointing to TIE2 inhibition as a more effective therapy than mTOR blockade.

Research Paper
May 22, 2026 0
Elevated Lipoprotein(a) Increases Blood Clot Risk in Premenopausal Women
Heart Health

Elevated Lipoprotein(a) Increases Blood Clot Risk in Premenopausal Women

Large UK study reveals elevated Lp(a) levels raise venous thromboembolism risk by 32% in premenopausal women but not in men or postmenopausal women.

Research Paper
Mar 30, 2026 0
9-Apolipoprotein Blood Panel Outperforms Standard Cholesterol Tests for Heart Attack Risk
Heart Health

9-Apolipoprotein Blood Panel Outperforms Standard Cholesterol Tests for Heart Attack Risk

A mass spectrometry apolipoprotein panel predicts cardiovascular events and identifies who gains the most from PCSK9 inhibitor therapy.

Research Paper
Jun 12, 2026 0
High Lipoprotein(a) Levels Drive Dangerous Coronary Plaque Growth and Rupture Risk
Heart Health

High Lipoprotein(a) Levels Drive Dangerous Coronary Plaque Growth and Rupture Risk

Meta-analysis of 19,822 people reveals elevated Lp(a) accelerates coronary plaque progression and creates rupture-prone plaques.

Research Paper
Mar 28, 2026 1
Scientists Discover Brain Protein Aggregation That Drives Alzheimer's Neurodegeneration
Heart Health

Scientists Discover Brain Protein Aggregation That Drives Alzheimer's Neurodegeneration

New research reveals how GRK2 protein clumping damages brain cells and identifies potential therapeutic targets to slow cognitive decline.

Research Paper
Mar 28, 2026 1
OxPL Biomarker Predicts Heart Attack Risk and Responds to Alirocumab
Heart Health

OxPL Biomarker Predicts Heart Attack Risk and Responds to Alirocumab

Elevated oxidized phospholipids independently predict major cardiac events after ACS, and alirocumab abolishes that risk signal.

Research Paper
Jun 4, 2026 0
Olpasiran Slashes Lp(a) Levels in Phase 2 Cardiovascular Trial
Heart Health

Olpasiran Slashes Lp(a) Levels in Phase 2 Cardiovascular Trial

Amgen's siRNA therapy olpasiran targets lipoprotein(a), a stubborn cardiovascular risk factor with no approved treatments.

Clinical Trial
Jun 14, 2026 0
Next-Generation Heart Test Could Revolutionize Early Cardiac Risk Detection
Heart Health

Next-Generation Heart Test Could Revolutionize Early Cardiac Risk Detection

New ultra-sensitive cardiac troponin T assay promises earlier, more accurate detection of heart muscle damage for better prevention.

Research Paper
Mar 28, 2026 0
Calcified Artery Plaques Still Harbor Active Lipids Despite Aggressive Cholesterol Lowering
Heart Health

Calcified Artery Plaques Still Harbor Active Lipids Despite Aggressive Cholesterol Lowering

New imaging reveals calcified plaques contain active lipid deposits that persist even with very low LDL cholesterol levels below 55 mg/dL.

Research Paper
Mar 29, 2026 0
Lipoprotein(a) and Hormones Create Dangerous Blood Clot Risk Combination
Heart Health

Lipoprotein(a) and Hormones Create Dangerous Blood Clot Risk Combination

New research reveals how elevated Lp(a) levels interact with hormonal changes to significantly increase venous thromboembolism risk.

Research Paper
Mar 30, 2026 0
Hidden Heart Risk Detected in Patients With Normal Cardiac Stress Tests
Heart Health

Hidden Heart Risk Detected in Patients With Normal Cardiac Stress Tests

A new PET imaging metric identifies patients with normal scans who still face 41% higher cardiovascular event risk.

Research Paper
Jun 6, 2026 0
New Blood Marker Predicts Heart Disease Risk in Early Metabolic Syndrome
Heart Health

New Blood Marker Predicts Heart Disease Risk in Early Metabolic Syndrome

CTI index combining inflammation and insulin resistance shows 111% higher death risk in 5,847 Chinese adults.

Research Paper
Apr 4, 2026 0
Advanced Heart Imaging Now Detects Hidden Fat Inflammation to Predict Heart Attacks
Heart Health

Advanced Heart Imaging Now Detects Hidden Fat Inflammation to Predict Heart Attacks

New CT scan technology can spot dangerous fat around arteries that predicts heart attacks better than traditional methods.

Research Paper
Mar 29, 2026 1
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