Biogen's Anti-Tau Alzheimer's Drug Misses Phase 2 But Shows Hints of Promise
BIIB080 failed its primary endpoint in Phase 2, yet Biogen sees potential signals worth pursuing in the fight against Alzheimer's tau tangles.
20 articles
BIIB080 failed its primary endpoint in Phase 2, yet Biogen sees potential signals worth pursuing in the fight against Alzheimer's tau tangles.
Scientists engineer high-PS procoagulant platelets that outperform thrombin and commercial hemostatic agents, even in antiplatelet-treated patients.
150-person trial tests whether PRP injections can reduce knee pain and improve function better than placebo in osteoarthritis patients.
Single-cell sequencing reveals ferroptosis drives pulpitis; thymosin ฮฑ1 restores GPX4, cuts iron overload, and reduces inflammation in cells and rats.
New trial tests whether PRP injections can reduce tennis elbow pain better than standard treatments in 72 participants.
New research reveals that targeting a specific toxic protein variant may be more effective than current Huntington's treatments.
Mitochondria-targeted antioxidant polymer shows superior protection against liver transplant injury compared to standard treatments.
Comprehensive analysis reveals why platelet-rich plasma outcomes vary and provides framework for standardization.
Clinical trial tests platelet-rich plasma therapy for shoulder osteoarthritis in 91 patients over 5 months.
New technique simultaneously tracks cell division and gene activity in living tissues, revealing hidden repair mechanisms.
Military study tests regenerative PRP injections against placebo for facet joint pain in 91 participants.
Small pilot study explores whether PRP injections can safely reverse aging signs in women's facial and hand skin.
Small trial tests blood-derived therapy for persistent post-surgical ear infections that resist standard treatments.
Revolutionary nanoneedle technology creates molecular replicas of living brain tissue, enabling repeated monitoring of glioma progression and treatment response.
Single injection of protective brain protein via gene therapy fully restored memory formation and dramatically reduced amyloid plaques.
Advanced protein analysis methods could revolutionize early disease detection and personalized medicine approaches.
A landmark multi-omics atlas of human kidney tissue reveals how proximal tubule cells shift between repair and disease states after injury.
BioNTech reports positive Phase 2 results for HER2-targeted cancer therapy, with FDA filing planned to compete with existing treatments.
Explore the molecular mechanisms of cellular senescence and how p16/p21 pathways drive SASP production, plus cutting-edge senolytic drug targets.
A landmark clinical trial transplanted iPSC-derived dopamine neurons into Parkinson's patients using only tacrolimus โ with no significant immune rejection.