20 articles
Researchers analyzed 2,911 proteins in 50,506 people to create a frailty score that predicts disease risk and biological aging.
New study shows DunedinPACE aging biomarker can predict who will develop metabolic syndrome years in advance, outperforming other epigenetic clocks.
Large NHANES study reveals metabolic syndrome causes measurable acceleration in epigenetic aging clocks, offering new targets for intervention.
Second-generation epigenetic clocks show strong associations with metabolic syndrome and type 2 diabetes risk prediction.
New cryo-EM structures reveal how LYCHOS protein senses cholesterol levels to regulate mTORC1 signaling, offering drug targets for aging.
A noninvasive 13-variable score reveals how fast your liver is aging — and accelerated liver aging raises mortality risk by up to 85%.
Large study reveals specific blood proteins can identify who will die from heart disease a decade before death occurs.
Large study reveals how gut microbe proteins shift with aging and contribute to diabetes and metabolic disorders.
A 6-month AI-driven personalized diet intervention cut BMI by 33% and reduced biological age by 8 years in morbidly obese patients.
Mice lacking the HDAC9 gene gained less fat with age, accumulated fewer senescent cells, and showed improved mitochondrial respiration in adipose tissue.
Researchers discover how disrupted circadian rhythms in fat cells impair mitochondrial function, leading to metabolic syndrome.
A comprehensive review reveals how obesity and aging converge through shared inflammatory biomarkers, accelerating disease risk in the elderly.
New research reveals how a key cellular protein prevents ferroptosis, a type of cell death implicated in aging and age-related diseases.
Restoring mitochondrial complex I function in fat cells prevents obesity-related metabolic dysfunction, even without weight loss.
New review reveals how saturated fat-rich diets trigger neuroinflammation and cognitive decline, but offers actionable prevention strategies.
Multi-omic analysis reveals GLP-1 receptor agonists counter aging processes across multiple organ systems and biological pathways.
Large-scale study identifies three key blood proteins that predict diabetic retinopathy development with 90% accuracy.
New research links NAD+ imbalance to RYR1-related muscle disorders, potentially revealing cellular aging pathways.
A mouse study reveals how aging and poor diet synergistically disrupt liver thyroid hormone metabolism, accelerating fatty liver disease — and why resmetirom may help.
A newly identified mitochondrial NAD transporter in fat cells controls whether you develop obesity and insulin resistance as you age.
