20 articles
New mouse research finds the trendy D+Q senolytic combo severely damages myelin, raising red flags for longevity self-experimenters.
Researchers identified the gene that transports queuosine, a micronutrient crucial for brain health and cancer defense, solving a decades-old mystery.
The SenNet atlas reveals where aging cells accumulate in human tissues, opening new doors for senolytic therapies and healthspan extension.
A molecule called OLE restores microglia's protective function, reducing amyloid plaques and improving memory in animal models.
Declining Menin in the hypothalamus drives inflammation and aging. Restoring it reversed decline; D-serine amino acid improved cognition in mice.
Arginine supplements reduced toxic amyloid buildup, brain inflammation, and behavioral decline in fly and mouse Alzheimer's models.
New compounds targeting the cPLA2 enzyme may reduce Alzheimer's-linked brain inflammation, especially in high-risk APOE4 gene carriers.
UCLA scientists discover why some neurons resist Alzheimer's better than others, revealing a natural protein cleanup system that could lead to new treatments.
Researchers finally discovered how lecanemab clears brain plaques by activating immune cells through a specific antibody fragment.
Researchers finally discovered lecanemab activates brain immune cells through a specific antibody fragment to clear toxic plaques.
Researchers turned ordinary brain cells into plaque-clearing machines, reducing Alzheimer's amyloid by half in mice with one treatment.
Buck Institute finds the longevity-linked APOE2 variant shields neurons from DNA damage and cellular senescence, explaining its Alzheimer's protection.
Raising Sox9 levels in aging astrocytes reduced amyloid plaque buildup and protected memory in mouse models with existing Alzheimer's symptoms.
Blocking the protein PTP1B boosted memory and cleared brain plaque in mice, with potential links to diabetes and obesity treatment.
New research identifies FTL1 protein as key driver of brain aging. Reducing it restored memory and neural connections in mice.
Major study identifies three existing drugs that could be repurposed to fight Alzheimer's disease, offering faster path to treatment.
A home-based walking and resistance program improved attention and reduced observable cognitive decline in chemotherapy patients over 6 weeks.
New gene therapy zorevunersen dramatically reduced seizures in children with severe Dravet syndrome epilepsy while improving quality of life.
Baylor scientists find tubulin redirects rogue brain proteins away from toxic aggregates, pointing to a novel neurodegenerative disease strategy.
A small trial found tocilizumab, an anti-inflammatory drug, cut depression remission rates better than SSRIs by targeting IL-6, not brain chemistry.
