20 articles
Expert reviews rank fisetin and quercetin as top senolytics, with spermidine and resveratrol as supporting players in longevity supplement stacks.
Expert reviews compare leading senolytic and NAD+ supplement brands on ingredients, evidence quality, and value.
A product review breaks down the evidence tiers for four popular longevity supplements and rates the best commercial stacks.
New review reveals how senescent cells both prevent and promote cancer, opening therapeutic opportunities.
Senescent macrophages and cell death pathways fuel atherosclerosis — and new drug targets may finally interrupt the cycle.
A new review reveals how senescent healthy cells within tumors quietly drive cancer progression and therapy resistance.
A sweeping review organizes 20 years of anti-aging pharmacology into three intervention axes and ranks the top compounds by research impact.
New research reveals how people over 100 maintain youthful immune systems despite chronic inflammation, offering insights for healthy aging.
Researchers outline innovative approaches to speed up drug development for age-related diseases and longevity interventions.
A new review maps the bidirectional crosstalk between gut microbiota and cellular senescence driving multi-organ degeneration.
Biomolecular condensates formed by liquid-liquid phase separation offer a new platform for clearing disease-causing proteins conventional drugs can't target.
Senescent T cells fuel psoriasis, eczema, and rosacea through toxic secretions. New therapies may finally break the cycle.
Independent testing reveals rampant quality failures in NMN, NR, and NAD+ supplements. Know what to look for before buying.
Expert reviews confirm NR and NMN raise blood NAD+, but longevity proof remains elusive and product quality varies widely.
A new Nature Metabolism review reveals how mitochondrial maintenance systems govern healthy aging — and how NAD+, AMPK, and caloric restriction may restore them.
New review links physical activity to glymphatic function — the brain's built-in detox network that flushes neurotoxic proteins.
A Cochrane meta-analysis of 17 RCTs finds amyloid-targeting antibodies offer minimal cognitive gains while significantly raising ARIA risk.
A new Cell Metabolism review from NIH identifies how ECM stiffening, poor blood flow, and mitochondrial failure lock tissues into accelerating decline.
A candid breakdown of top NAD+ booster brands reveals strong biomarker data but slim evidence for real longevity outcomes.
Independent testing exposes widespread quality failures in NAD+ precursor supplements, with actionable guidance on which brands actually deliver.
