73 articles
A systematic review of 27 human trials finds calorie restriction best modulates senescence markers, but direct evidence remains elusive.
A systematic review of 90 studies reveals mTOR both drives MS inflammation and is essential for myelin repair — complicating treatment strategies.
A comprehensive 2025 review maps the mechanisms behind MSC senescence and surveys emerging rejuvenation strategies for cell-based therapies.
A short-term drug combo rejuvenates aged mesenchymal stem cells, boosting proliferation and reducing inflammatory markers in vitro.
A traditional Chinese formula and its key compound GsRg1 restore brain insulin signaling in obese rats by activating hypothalamic self-cleaning pathways.
A comprehensive review maps the molecular drivers of ovarian aging and surveys emerging interventions that may delay or reverse reproductive decline in women.
A new nanoparticle system delivers rapamycin and a DNA scavenger directly to arterial plaques, cutting inflammation and improving plaque stability in mice.
Mike Lustgarten explores using cellular testing to screen longevity interventions personally before committing to them.
Bioinformatician David Meyer explains how stochastic DNA changes power aging clocks and what that means for rejuvenation.
A new review reframes epigenetic clocks as direct readouts of epigenetic drift, deepening our understanding of biological aging measurement.
A longevity biotech targets skin aging via TORC1 modulation, raising $20M to commercialize its Re-Q serum backed by serious geroscience.
New research reveals antioxidants can selectively eliminate senescent muscle cells by correcting faulty mTOR nutrient-sensing pathways linked to aging.
