SGLT2 Inhibitors Deliver Far More Than Blood Sugar Control
A major review reveals how SGLT2 inhibitors protect the heart, kidneys, and metabolism through at least seven distinct biological mechanisms.
20 articles
A major review reveals how SGLT2 inhibitors protect the heart, kidneys, and metabolism through at least seven distinct biological mechanisms.
Real-world study of 1,559 octogenarians finds SGLT2 inhibitors reduce all-cause death by 42% and heart failure rehospitalization by 31% with no increase in adverse events.
Mayo Clinic tests whether 6 months of the SGLT2 inhibitor dapagliflozin can reduce exercise-induced cardiac pressure in preserved-ejection-fraction heart failure.
Dive deep into the molecular mechanisms of vascular aging and explore cutting-edge interventions — from senolytic therapies and nitric oxide restoration to exercise-induced remodeling and emerging pharmacological approaches — that are redefining what's possible in cardiovascular longevity.
New analysis reveals oral semaglutide significantly reduces cardiovascular risk factors beyond blood sugar control in type 2 diabetes.
A new meta-analysis of 37,393 patients finds GLP-1 receptor agonists may reduce mortality and major cardiac events in type 2 diabetics with prior MI.
New research reveals GLP-1 receptor agonists could significantly reduce cardiovascular risk in broader patient populations.
New research suggests GLP-1 drugs could maintain benefits with reduced dosing frequency, potentially improving convenience and adherence.
A pill-form GLP-1 receptor agonist significantly reduced multiple cardiovascular risk markers in both T2D and obesity patients over 26–36 weeks.
New evidence suggests oral semaglutide sustains long-term improvements in key CVD risk factors, expanding its role beyond diabetes management.
New oral formulations of popular GLP-1 medications may eliminate the need for weekly injections while maintaining benefits.
New VA database analysis sheds light on the contested link between GLP-1 receptor agonists and pancreatitis risk.
Health authorities issue new warnings as reports of fatal pancreatitis cases increase among GLP-1 drug users.
Major study shows tirzepatide reduces cardiovascular and kidney complications by 16% compared to dulaglutide in diabetic patients.
GLP-1 drug semaglutide demonstrates potential benefits for Alzheimer's patients following major clinical trial results.
New research shows tirzepatide doesn't surpass dulaglutide's cardiovascular benefits despite being a newer diabetes medication.
Real-world registry data shows 54% of coronary artery disease patients meet eligibility criteria for semaglutide based on SELECT and SOUL trial standards.
Learn what glucose and ketones in your urine actually mean for your metabolic health and diabetes risk.
New research shows GLP-1 medications primarily burn fat while maintaining muscle strength and improving overall body composition.
Large clinical trial finds popular diabetes drug semaglutide ineffective at slowing Alzheimer's progression in early-stage patients.
A real-world study of 37,000+ matched patients finds GLP-1 receptor agonists dramatically reduce cardiovascular events in obese adults with OSA.