91 articles
A natural flavonoid found in fruits clears senescent cells and restores artery function damaged by doxorubicin chemotherapy in mice.
The European Innovation Council is offering up to €4M per project to turn aging research into real therapies. Deadline: October 2026.
A new review reframes epigenetic clocks as direct readouts of epigenetic drift, deepening our understanding of biological aging measurement.
New research reveals how aging transforms protective immune cells into drivers of inflammation, senescence, and tissue damage.
A new Nature Communications study identifies NRF1 as a master driver of inflammaging via the TBK1/IRF3 innate immune axis.
A new review maps the molecular mechanisms behind liver aging and evaluates dietary, drug, and gene-editing interventions to slow decline.
A landmark 2025 review maps every mechanism behind arterial stiffness—and charts a clear path toward prevention and therapy.
A landmark review synthesizes 12 hallmarks of aging, emerging gerotherapeutics, and a new three-tier clinical care model to shift medicine from disease treatment to aging prevention.
A comprehensive review reveals metformin's polypharmacological mechanisms—from AMPK activation to gut microbiome remodeling—that may delay aging and enhance cancer immunotherapy.
New research reveals antioxidants can selectively eliminate senescent muscle cells by correcting faulty mTOR nutrient-sensing pathways linked to aging.
The SenNet atlas reveals where aging cells accumulate in human tissues, opening new doors for senolytic therapies and healthspan extension.
A dual therapy clearing senescent cells and restoring stem cell function dramatically extended mouse lifespan in a new preclinical study.
