Why Your Arteries Stiffen With Age and How to Fight Back
A landmark 2025 review maps every mechanism behind arterial stiffness—and charts a clear path toward prevention and therapy.
56 articles
A landmark 2025 review maps every mechanism behind arterial stiffness—and charts a clear path toward prevention and therapy.
A landmark review synthesizes 12 hallmarks of aging, emerging gerotherapeutics, and a new three-tier clinical care model to shift medicine from disease treatment to aging prevention.
A comprehensive review reveals metformin's polypharmacological mechanisms—from AMPK activation to gut microbiome remodeling—that may delay aging and enhance cancer immunotherapy.
New research reveals antioxidants can selectively eliminate senescent muscle cells by correcting faulty mTOR nutrient-sensing pathways linked to aging.
The SenNet atlas reveals where aging cells accumulate in human tissues, opening new doors for senolytic therapies and healthspan extension.
A dual therapy clearing senescent cells and restoring stem cell function dramatically extended mouse lifespan in a new preclinical study.
A landmark NIH study creates the first comprehensive atlas of senescent cells, reshaping our understanding of aging biology and healthspan.
A landmark single-cell study maps how dasatinib + quercetin reshapes aging across multiple tissues, revealing timing matters as much as the drug itself.
Discover how 'zombie cells' in your body send harmful signals that spread aging from cell to cell — and what scientists are doing to stop them.
A medicinal-chemistry optimized flavonol called F-4N shows 50× greater senolytic potency than quercetin and resolves lung fibrosis in animal models.
New research reveals how aging senescent cells drive angiogenesis in gut cancers, undermining standard anti-VEGF treatments.
Clearing zombie cells then restoring stem cell activity produced far greater lifespan gains than either approach alone.