NIH Maps First Large-Scale Atlas of Senescent Cells Across the Human Body
The SenNet atlas reveals where aging cells accumulate in human tissues, opening new doors for senolytic therapies and healthspan extension.
20 articles
The SenNet atlas reveals where aging cells accumulate in human tissues, opening new doors for senolytic therapies and healthspan extension.
Cambridge researchers found a gene network that shuts off nerve repair — and an existing hormone drug that reactivates it.
Clinical trial shows solriamfetol significantly improves alertness and performance in workers who start before sunrise.
UC Berkeley researchers discovered brain circuits linking deep sleep to growth hormone release, revealing how sleep builds muscle and burns fat.
Declining Menin in the hypothalamus drives inflammation and aging. Restoring it reversed decline; D-serine amino acid improved cognition in mice.
New brain-targeted gene therapy mimics morphine's pain relief while avoiding addiction, offering hope for 50+ million Americans with chronic pain.
New technique maps thousands of neural connections simultaneously, potentially revolutionizing understanding of brain aging and disease.
A molecule called OLE restores microglia's protective function, reducing amyloid plaques and improving memory in animal models.
New NIH research reveals the brain-cell signaling mechanism behind GLP-1 drug plateaus and a potential way to extend their effects.
Johns Hopkins scientists found brainstem neurons that filter distractions in mice, offering new clues to treating ADHD and attention disorders.
UC Davis scientists created novel brain-healing molecules that activate key serotonin receptors tied to neuroplasticity — without triggering hallucinations.
New mouse research finds the trendy D+Q senolytic combo severely damages myelin, raising red flags for longevity self-experimenters.
MIT researchers discovered that 30% of adult brain synapses are dormant but ready to activate, reshaping how we understand lifelong learning.
Duke researchers restored healthy mitochondria to damaged nerve cells, cutting pain-related behaviors by 50% in mice with nerve pain.
New study reveals two-thirds of daily behaviors are automatic habits, offering insights for building healthier routines and breaking bad ones.
A study of 100,000 people found semaglutide users had 44% lower depression risk and 42% fewer psychiatric hospitalizations.
New research reveals GLP-1 drugs like Ozempic significantly reduce depression, anxiety, and substance use disorders alongside weight management.
Early-life exposure to DEHP, a plasticizer in everyday products, caused lasting anxiety in male rats — and GABA or testosterone reversed it.
A new tool that boosts mitochondrial activity in neurons restored memory in dementia mice, suggesting energy failure drives Alzheimer's symptoms.
Stanford researchers found ribosome stalling in aging brain cells triggers faulty proteins and toxic clumps linked to Alzheimer's disease.