Metabolic Health
EDP-305 Targets NASH in Phase 2 Trial Testing Two Doses Against Placebo
Enanta Pharmaceuticals tests its FXR agonist EDP-305 in a completed Phase 2 randomized trial for non-alcoholic steatohepatitis.
Clinical Trial
Jun 18, 2026 0
Results for "Senomorphics" in Diabetes
20 articles
Metabolic Health
Calorie Restriction Reverses Hidden Metabolic Dysfunction in Normal Weight Adults
Study reveals how lean people can still have obesity-like metabolism and whether calorie restriction helps reverse this dangerous condition.
Clinical Trial
Mar 29, 2026 1
Metabolic Health
NAD Precursor Combo Tested to Boost Muscle Mitochondria in Elderly Adults
Maastricht University investigated whether NA, NAM, and tryptophan together could restore mitochondrial function in physically compromised older adults.
Clinical Trial
May 8, 2026 0
Metabolic Health
Thorne's Quercetin Phytosome Trial for Metabolic Health Was Terminated Early
A sponsored 90-day trial of enhanced-absorption quercetin targeting cholesterol, blood sugar, and metabolic age was terminated before completion.
Clinical Trial
Jun 24, 2026 0
Metabolic Health
Takeda Tests TAK-510 Safety in First Human Trial for Nausea and Vomiting
Takeda's Phase 1 trial evaluates the safety and tolerability of TAK-510, a novel injectable agent targeting nausea and vomiting, across escalating doses.
Clinical Trial
Jun 12, 2026 0
Metabolic Health
Can Two Weeks of Exercise Restore Mitochondrial Quality Control? (Trial Registration)
A completed OSU trial investigates whether short-term exercise training can restore impaired mitochondrial cleanup pathways in overweight and obese skeletal muscle.
Clinical Trial
Jun 15, 2026 0
Metabolic Health
CT-868 Dual Agonist Targets Blood Sugar and Obesity in Phase 2 Diabetes Trial
Carmot Therapeutics tests CT-868, a novel dual incretin receptor agonist, for HbA1c reduction in overweight and obese adults with poorly controlled T2DM.
Clinical Trial
Jun 16, 2026 0
Metabolic Health
Precision Nutrition Study Reveals How Individual Bodies Respond to Carbs and Fasting
176-person study explored personalized responses to refined carbs, whole grains, and intermittent fasting for optimal glucose control.
Clinical Trial
Mar 28, 2026 2
Metabolic Health
RNA Drug Targets ANGPTL3 to Slash Triglycerides in Rare Fat Disorder
A Phase 2 trial tests a GalNAc-conjugated antisense therapy in familial partial lipodystrophy patients with dangerously high triglycerides.
Clinical Trial
Jun 23, 2026 0
Metabolic Health
Six Weeks of Endurance Training Activates Brown Fat for Better Metabolism
New study reveals how endurance exercise transforms fat-burning brown adipose tissue in just six weeks of training.
Clinical Trial
Mar 29, 2026 0
Metabolic Health
Exercise Order Matters for Women with Severe Obesity Fighting Metabolic Syndrome
20-week study reveals how sequencing HIIT and resistance training affects metabolic health in women with morbid obesity.
Clinical Trial
Mar 29, 2026 1
Metabolic Health
16-Hour Overnight Fast Boosts Muscle Protein Building in Small University Study
New research suggests extending overnight fasting from 10 to 16 hours may enhance muscle's ability to use dietary protein for growth.
Clinical Trial
Mar 29, 2026 1
Metabolic Health
Bariatric Surgery Shows Lasting Metabolic Benefits Beyond Weight Loss in 2-Year Study
43-patient study tracked metabolic changes for 2 years after bariatric surgery, revealing improvements beyond simple weight reduction.
Clinical Trial
Mar 28, 2026 1
Metabolic Health
Scientists Discover How Fat Tissue Controls Whole-Body Insulin Resistance
Swiss researchers studied how mTOR protein in fat tissue affects metabolism and insulin function throughout the body.
Clinical Trial
Mar 28, 2026 0
Metabolic Health
PCSK9 Inhibitor Alirocumab Outperforms Usual Care in Diabetic Mixed Dyslipidemia
Phase 4 trial tests whether alirocumab can better control non-HDL cholesterol in high-risk type 2 diabetics failing statin therapy.
Clinical Trial
Jun 16, 2026 0
Metabolic Health
Fasting and Ketogenic Diet Reset Fat Production Pathways in Obese Adults
Czech study reveals how strategic fasting and ketogenic diets can reprogram harmful fat production in obesity.
Clinical Trial
Mar 29, 2026 1
Metabolic Health
Muscle Mitochondrial Defects Mapped as Root Cause of Genetic Insulin Resistance
A Danish case-control trial uses gold-standard metabolic testing to uncover how mtDNA mutations impair muscle glucose uptake and drive insulin resistance.
Clinical Trial
Jun 16, 2026 0
Metabolic Health
Triple Therapy Targets Diabetes and Muscle Loss in Elderly Adults
Mediterranean diet, resistance training, and diabetes medication combined to combat sarcopenia and improve metabolic health in older adults.
Clinical Trial
Mar 28, 2026 1
Metabolic Health
Vegetarian vs Non-Vegetarian Diets Show Different Health Profiles in Active Adults
Cross-sectional study of 93 healthy adults compared cardiovascular risk factors between vegetarian and non-vegetarian dietary patterns.
Clinical Trial
Mar 28, 2026 1
Metabolic Health
Age Changes How Cancer Affects Metabolism in Elderly Lung Cancer Patients
French study reveals how aging influences metabolic responses to cancer, potentially explaining malnutrition patterns in elderly patients.
Clinical Trial
Mar 28, 2026 1
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