20 articles
A new oligonucleotide probe workflow recovers complete RSV and norovirus genomes from low-titer clinical samples, transforming viral surveillance.
Researchers analyzed over 1 million brain cells to create the first comprehensive map of microglia across diseases.
Comprehensive review explores how combining genomics, proteomics, and metabolomics advances psoriasis understanding and treatment.
New spatial multiomics study maps cellular interactions in systemic sclerosis, revealing fibroblast-macrophage dynamics.
Massive genetic analysis of 25 populations uncovers immune system variations that could explain differences in infection susceptibility.
Cutting-edge genomic and immune profiling techniques uncover promising pathways for treating this chronic autoimmune condition.
Advanced genetic analysis reveals new pathways to personalized RA therapy, addressing treatment failures in 30-40% of patients.
Researchers modified NK and T cells with special receptors that help them track down and infiltrate solid tumors more effectively.
Structural biology uncovers the exact amino acid motif causing species-specific drug failures, enabling transgenic mouse models for better P2X7 drug testing.
Whole genome sequencing of 7,339 Chinese participants uncovers novel genetic variants affecting serum uric acid, opening doors for precision therapies.
Researchers analyzed 38 immune system structures to develop AI-powered, personalized treatments for autoimmune diseases.
Researchers identify how TSLP protein creates regulatory T cells that suppress immune responses in melanoma.
A completed Phase 3 trial tests placental MSC secretome injections against placebo in 60 GvHD patients at an Iranian hospital.
A mechanistic deep-dive into cutting-edge anti-inflammaging interventions — from senolytic pharmacology and precision cytokine targeting to partial reprogramming strategies that aim to restore youthful immune homeostasis.
Scientists used CRISPR to find SPART, a human gene that restricts a whole family of dangerous flaviviruses including Zika and dengue.
Researchers identify the molecular mechanism controlling STING protein trafficking, revealing new targets for cancer immunotherapy.
New research reveals how metabolic molecules function as signaling agents that control immune responses within tumors.
A blinded head-to-head comparison finds a fully automated single-copy RNA assay detects residual HIV in over 57% of suppressed patients, versus ≤40% for manual methods.
Researchers identified specific lupus patient subgroups who respond dramatically better to baricitinib using gene expression analysis.
New research reveals how RNA-binding proteins orchestrate immune responses, offering insights into preventing chronic inflammation.
