Results for "Spatial Transcriptomics" in Diabetes

20 articles

RNA Drug Targets ANGPTL3 to Slash Triglycerides in Rare Fat Disorder
Metabolic Health

RNA Drug Targets ANGPTL3 to Slash Triglycerides in Rare Fat Disorder

A Phase 2 trial tests a GalNAc-conjugated antisense therapy in familial partial lipodystrophy patients with dangerously high triglycerides.

Clinical Trial
Jun 23, 2026 0
Precision Nutrition Study Reveals How Individual Bodies Respond to Carbs and Fasting
Metabolic Health

Precision Nutrition Study Reveals How Individual Bodies Respond to Carbs and Fasting

176-person study explored personalized responses to refined carbs, whole grains, and intermittent fasting for optimal glucose control.

Clinical Trial
Mar 28, 2026 2
Emory Study Maps the Best Blood Draw Timing After Fat and Sugar Meals
Metabolic Health

Emory Study Maps the Best Blood Draw Timing After Fat and Sugar Meals

Researchers test lipid, glucose, and mixed meal challenges to pinpoint optimal post-meal sample collection windows for future cardiovascular studies.

Clinical Trial
Jun 15, 2026 0
Thorne's Quercetin Phytosome Trial for Metabolic Health Was Terminated Early
Metabolic Health

Thorne's Quercetin Phytosome Trial for Metabolic Health Was Terminated Early

A sponsored 90-day trial of enhanced-absorption quercetin targeting cholesterol, blood sugar, and metabolic age was terminated before completion.

Clinical Trial
Jun 24, 2026 0
Muscle Mitochondrial Defects Mapped as Root Cause of Genetic Insulin Resistance
Metabolic Health

Muscle Mitochondrial Defects Mapped as Root Cause of Genetic Insulin Resistance

A Danish case-control trial uses gold-standard metabolic testing to uncover how mtDNA mutations impair muscle glucose uptake and drive insulin resistance.

Clinical Trial
Jun 16, 2026 0
Vegetarian vs Non-Vegetarian Diets Show Different Health Profiles in Active Adults
Metabolic Health

Vegetarian vs Non-Vegetarian Diets Show Different Health Profiles in Active Adults

Cross-sectional study of 93 healthy adults compared cardiovascular risk factors between vegetarian and non-vegetarian dietary patterns.

Clinical Trial
Mar 28, 2026 1
Scientists Discover How Fat Tissue Controls Whole-Body Insulin Resistance
Metabolic Health

Scientists Discover How Fat Tissue Controls Whole-Body Insulin Resistance

Swiss researchers studied how mTOR protein in fat tissue affects metabolism and insulin function throughout the body.

Clinical Trial
Mar 28, 2026 0
Small-Sided Football Games Tested as Hybrid Exercise Therapy for Type 2 Diabetes
Metabolic Health

Small-Sided Football Games Tested as Hybrid Exercise Therapy for Type 2 Diabetes

A completed RCT tests whether small-sided football sessions 3x/week improve glucose control and metabolic health in T2DM patients on GLP-1 and SGLT2 drugs.

Clinical Trial
Jun 14, 2026 0
Exercise Order Matters for Women with Severe Obesity Fighting Metabolic Syndrome
Metabolic Health

Exercise Order Matters for Women with Severe Obesity Fighting Metabolic Syndrome

20-week study reveals how sequencing HIIT and resistance training affects metabolic health in women with morbid obesity.

Clinical Trial
Mar 29, 2026 1
CT-868 Dual Agonist Targets Blood Sugar and Obesity in Phase 2 Diabetes Trial
Metabolic Health

CT-868 Dual Agonist Targets Blood Sugar and Obesity in Phase 2 Diabetes Trial

Carmot Therapeutics tests CT-868, a novel dual incretin receptor agonist, for HbA1c reduction in overweight and obese adults with poorly controlled T2DM.

Clinical Trial
Jun 16, 2026 0
IL-6 Blockade Reshapes How the Body Stores Fat After Meals
Metabolic Health

IL-6 Blockade Reshapes How the Body Stores Fat After Meals

A completed Danish trial investigates how blocking IL-6 signaling with tocilizumab alters fat, glucose, and protein metabolism in humans.

Clinical Trial
Jun 16, 2026 0
Can Two Weeks of Exercise Restore Mitochondrial Quality Control? (Trial Registration)
Metabolic Health

Can Two Weeks of Exercise Restore Mitochondrial Quality Control? (Trial Registration)

A completed OSU trial investigates whether short-term exercise training can restore impaired mitochondrial cleanup pathways in overweight and obese skeletal muscle.

Clinical Trial
Jun 15, 2026 0
EDP-305 Targets NASH in Phase 2 Trial Testing Two Doses Against Placebo
Metabolic Health

EDP-305 Targets NASH in Phase 2 Trial Testing Two Doses Against Placebo

Enanta Pharmaceuticals tests its FXR agonist EDP-305 in a completed Phase 2 randomized trial for non-alcoholic steatohepatitis.

Clinical Trial
Jun 18, 2026 0
Intermittent Fasting and Low-Carb Diets Show Promise for Reversing Metabolic Syndrome
Metabolic Health

Intermittent Fasting and Low-Carb Diets Show Promise for Reversing Metabolic Syndrome

169-person study tests whether intermittent fasting and low-carb approaches can reverse insulin resistance and metabolic dysfunction.

Clinical Trial
Mar 28, 2026 0
New Drug GFT505 Shows Promise for Fatty Liver Disease in Phase IIb Trial
Metabolic Health

New Drug GFT505 Shows Promise for Fatty Liver Disease in Phase IIb Trial

275-patient study tests novel liver-targeted therapy for NASH, a serious form of fatty liver disease affecting millions worldwide.

Clinical Trial
Mar 28, 2026 2
Six Weeks of Endurance Training Activates Brown Fat for Better Metabolism
Metabolic Health

Six Weeks of Endurance Training Activates Brown Fat for Better Metabolism

New study reveals how endurance exercise transforms fat-burning brown adipose tissue in just six weeks of training.

Clinical Trial
Mar 29, 2026 0
Common Medications May Block Vitamin B1 Absorption in Small Clinical Trial
Metabolic Health

Common Medications May Block Vitamin B1 Absorption in Small Clinical Trial

UCSF study reveals how metformin and trimethoprim interfere with thiamine uptake, potentially affecting energy metabolism.

Clinical Trial
Mar 29, 2026 2
Metformin Study Explores Insulin-Testosterone Link in Postmenopausal Women
Metabolic Health

Metformin Study Explores Insulin-Testosterone Link in Postmenopausal Women

University of Pennsylvania researchers investigated how insulin resistance and testosterone interact in women after menopause.

Clinical Trial
Mar 28, 2026 1
Time-Restricted Eating Shows Promise for Metabolically Unhealthy Obesity
Metabolic Health

Time-Restricted Eating Shows Promise for Metabolically Unhealthy Obesity

16-week study explores how 8-hour eating windows affect different types of obesity and metabolic health markers.

Clinical Trial
Mar 29, 2026 1
Bariatric Surgery Shows Lasting Metabolic Benefits Beyond Weight Loss in 2-Year Study
Metabolic Health

Bariatric Surgery Shows Lasting Metabolic Benefits Beyond Weight Loss in 2-Year Study

43-patient study tracked metabolic changes for 2 years after bariatric surgery, revealing improvements beyond simple weight reduction.

Clinical Trial
Mar 28, 2026 1
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