RNA Drug Targets ANGPTL3 to Slash Triglycerides in Rare Fat Disorder
A Phase 2 trial tests a GalNAc-conjugated antisense therapy in familial partial lipodystrophy patients with dangerously high triglycerides.
20 articles
A Phase 2 trial tests a GalNAc-conjugated antisense therapy in familial partial lipodystrophy patients with dangerously high triglycerides.
176-person study explored personalized responses to refined carbs, whole grains, and intermittent fasting for optimal glucose control.
Researchers test lipid, glucose, and mixed meal challenges to pinpoint optimal post-meal sample collection windows for future cardiovascular studies.
A sponsored 90-day trial of enhanced-absorption quercetin targeting cholesterol, blood sugar, and metabolic age was terminated before completion.
A Danish case-control trial uses gold-standard metabolic testing to uncover how mtDNA mutations impair muscle glucose uptake and drive insulin resistance.
Cross-sectional study of 93 healthy adults compared cardiovascular risk factors between vegetarian and non-vegetarian dietary patterns.
Swiss researchers studied how mTOR protein in fat tissue affects metabolism and insulin function throughout the body.
A completed RCT tests whether small-sided football sessions 3x/week improve glucose control and metabolic health in T2DM patients on GLP-1 and SGLT2 drugs.
20-week study reveals how sequencing HIIT and resistance training affects metabolic health in women with morbid obesity.
Carmot Therapeutics tests CT-868, a novel dual incretin receptor agonist, for HbA1c reduction in overweight and obese adults with poorly controlled T2DM.
A completed Danish trial investigates how blocking IL-6 signaling with tocilizumab alters fat, glucose, and protein metabolism in humans.
A completed OSU trial investigates whether short-term exercise training can restore impaired mitochondrial cleanup pathways in overweight and obese skeletal muscle.
Enanta Pharmaceuticals tests its FXR agonist EDP-305 in a completed Phase 2 randomized trial for non-alcoholic steatohepatitis.
169-person study tests whether intermittent fasting and low-carb approaches can reverse insulin resistance and metabolic dysfunction.
275-patient study tests novel liver-targeted therapy for NASH, a serious form of fatty liver disease affecting millions worldwide.
New study reveals how endurance exercise transforms fat-burning brown adipose tissue in just six weeks of training.
UCSF study reveals how metformin and trimethoprim interfere with thiamine uptake, potentially affecting energy metabolism.
University of Pennsylvania researchers investigated how insulin resistance and testosterone interact in women after menopause.
16-week study explores how 8-hour eating windows affect different types of obesity and metabolic health markers.
43-patient study tracked metabolic changes for 2 years after bariatric surgery, revealing improvements beyond simple weight reduction.