Brain Health
Flavonoid Supplement Shows Promise for Cognitive Function in Elderly Adults
Italian researchers test plant-based compounds for brain health and quality of life in aging adults with promising early results.
Clinical Trial
Mar 28, 2026 2
Results for "Spermidine" in Alzheimer's
20 articles
Brain Health
Pimavanserin Shows Promise for Preventing Dementia Psychosis Relapse in Clinical Trial
Study tested whether pimavanserin could prevent return of hallucinations and delusions in dementia patients who initially responded to treatment.
Clinical Trial
Mar 29, 2026 0
Brain Health
Drugs That Boost Brain Waste Clearance During Sleep Show Promise Against Alzheimer's
A Phase 1/2 trial tests whether dexmedetomidine can enhance the brain's glymphatic system to clear amyloid and tau during sleep.
Clinical Trial
May 16, 2026 0
Brain Health
Carnosine Supplement Targets Neuromuscular Decline in Multiple Sclerosis
A completed pilot trial tests whether 2g/day of a novel carnosine formulation can restore neuromuscular function and quality of life in MS patients.
Clinical Trial
Jun 17, 2026 0
Brain Health
Phase 1 Trial Maps How NR and NMN Reach the Brain After Supplementation
A completed pharmacokinetic study tracks NAD precursors NR and NMN from bloodstream to brain, filling a critical gap in human data.
Clinical Trial
May 12, 2026 0
Brain Health
Dasatinib and Quercetin Reach the Brain in Early Alzheimer's Patients
A completed Phase 1/2 pilot trial tested whether the senolytic duo D+Q penetrates the brain in early Alzheimer's disease.
Clinical Trial
May 28, 2026 0
Brain Health
Cilostazol Tested Against Cognitive Decline in Mild Cognitive Impairment
A Phase 2 trial explores whether cilostazol, a blood thinner with brain-protective effects, can slow memory loss in MCI patients.
Clinical Trial
Jun 27, 2026 0
Brain Health
Simufilam Alzheimer's Trial Terminated Before Completing Phase 3
Cassava Sciences' 76-week Phase 3 trial of simufilam for Alzheimer's was terminated, raising questions about the drug's future.
Clinical Trial
Jun 1, 2026 0
Brain Health
Microdosing Psilocybin Shows Promise for Major Depression in Clinical Trial
Small doses of psilocybin tested against placebo in 39 adults with major depressive disorder to assess safety and mood benefits.
Clinical Trial
Mar 29, 2026 0
Brain Health
Gamma Interferon Pilot Trial Tests Frataxin Boost in Friedreich Ataxia Patients
A Phase 2 open-label trial explores whether an approved immune drug can raise frataxin protein levels and slow neurological decline in Friedreich Ataxia.
Clinical Trial
Jun 16, 2026 0
Brain Health
Repurposed Anti-Nausea Drug TEP Tested for Clearing Alzheimer's Brain Plaques
A Phase 2 trial investigates whether thiethylperazine, a decades-old antiemetic, can flush toxic amyloid beta from the brains of early AD patients.
Clinical Trial
Jun 12, 2026 0
Brain Health
New Drug Shows Promise in Preventing Alzheimer's Amyloid Buildup in Young Adults
NGP 555 targets toxic brain protein production in healthy volunteers, offering potential early intervention for Alzheimer's prevention.
Clinical Trial
Mar 28, 2026 0
Brain Health
New Alzheimer's Drug BMS-984923 Completes Safety Testing in 51 Participants
Phase 1b trial tests escalating doses of experimental Alzheimer's treatment BMS-984923 for safety and tolerability in older adults.
Clinical Trial
Mar 28, 2026 1
Brain Health
SSRI Antidepressants May Block Psychedelic Effects by Reducing Brain Receptors
Swiss researchers tested whether paroxetine reduces LSD response by downregulating serotonin receptors in healthy adults.
Clinical Trial
Mar 28, 2026 1
Brain Health
Rapastinel Shows Lower Abuse Potential Than Ketamine in Phase 1 Trial
A completed Phase 1 trial compared the abuse liability of rapastinel versus ketamine in recreational polydrug users, with implications for safer depression treatment.
Clinical Trial
Jun 5, 2026 0
Brain Health
Nordic Berries Put to the Test for Fighting Age-Related Cognitive Decline
A completed trial tests whether daily Nordic berry beverages can sharpen cognition in healthy adults over 12 weeks.
Clinical Trial
Jun 14, 2026 0
Brain Health
Psilocybin Shows Promise for Treatment-Resistant Depression in Clinical Trial
Small study tests psychedelic compound's safety and effectiveness against severe depression that doesn't respond to standard treatments.
Clinical Trial
Mar 28, 2026 1
Brain Health
PET Imaging Study Maps Serotonin Receptor Changes in Parkinson's Disease
Completed French trial uses advanced brain imaging to track 5-HT4 serotonin receptors in Parkinson's patients, linking genetics to cognitive and mood changes.
Clinical Trial
Jun 27, 2026 0
Brain Health
Alpha-Lipoic Acid Added to Flunarizine Tested for Teen Migraine Prevention
A completed Phase 4 trial from India evaluates whether ALA supplementation boosts flunarizine's migraine-prevention power in adolescents.
Clinical Trial
Jun 17, 2026 0
Brain Health
Oral All-D-Peptide Contraloid Advances to Human Safety Trial for Alzheimer's
A first-in-human multiple-ascending-dose trial tests Contraloid, an oral peptide designed to disassemble toxic amyloid-beta oligomers linked to Alzheimer's disease.
Clinical Trial
Jun 17, 2026 0
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