Metabolic Health
Magnesium Controls Cellular Energy and May Slow the Pace of Aging
A new review reframes magnesium as a master regulator of mitochondrial energy, metabolic disease, and biological aging.
Review
Jun 6, 2026 0
Results for "Spermidine" in Diabetes
20 articles
Metabolic Health
How Mitochondrial Quality Control Shapes Human Aging and Longevity
A new Nature Metabolism review reveals how mitochondrial maintenance systems govern healthy aging — and how NAD+, AMPK, and caloric restriction may restore them.
Review
Jun 30, 2026 0
Metabolic Health
GLP-1 Drugs May Restore Eye Surface Health While Reshaping Facial Anatomy
Semaglutide and liraglutide show promise for dry eye and corneal repair, but may cause periocular volume loss that affects blinking and tear distribution.
Review
Jun 29, 2026 0
Metabolic Health
Tirzepatide Acts on Eight Organ Systems to Tackle Metabolic Disease
A new review maps how tirzepatide's dual GIP/GLP-1 action reshapes metabolism across the pancreas, liver, gut, heart, kidneys, and brain.
Review
Jul 2, 2026 0
Metabolic Health
Amylin Links Type 2 Diabetes to Alzheimer's and Parkinson's Disease
A major review repositions type 2 diabetes as a proteinopathy, with amylin aggregation bridging metabolic decline and neurodegeneration.
Review
Jul 3, 2026 0
Metabolic Health
Metabolism Controls How and When Cells Die — and Could Be Targeted in Disease
A major review proposes that cellular metabolism acts as a master gatekeeper of cell death, with implications for cancer, aging, and chronic disease.
Review
Jun 26, 2026 0
Metabolic Health
GLP-1 Drugs Work Better When Paired With Exercise and Nutrition Support
A new review argues that combining GLP-1 receptor agonists with structured exercise and dietary support preserves muscle and delivers lasting fat loss.
Review
Jun 28, 2026 0
Metabolic Health
Lactate and Ketones Form a Hidden Redox Circuit Linking Organs and Fighting Disease
A new framework reveals how lactate and β-hydroxybutyrate team up across organs to regulate metabolism, mitochondria, and disease.
Review
Jun 29, 2026 0
Metabolic Health
Why Aging Fat Tissue Undermines Metabolism and How to Fix It
Aging adipose tissue loses its ability to generate new fat cells, driving insulin resistance. New review maps the molecular culprits and best treatment options.
Review
Jun 29, 2026 0
Metabolic Health
Liver Support Systems Show No Clear Survival Benefit in Acute Liver Failure
A Cochrane meta-analysis of 11 RCTs finds very low-certainty evidence that liver support systems neither reduce mortality nor improve key outcomes in ALF.
Review
May 1, 2026 0
Metabolic Health
GLP-1 Drugs Show Real Promise for Obese Kids and Teens With Type 2 Diabetes
A systematic review of 13 studies finds semaglutide and liraglutide meaningfully cut BMI and improve blood sugar in children and adolescents.
Review
Jun 29, 2026 0
Metabolic Health
GLP-1 Drugs and Metformin Trim BMI in Obese Youth but Long-Term Safety Remains Unknown
A Cochrane review of 37 RCTs finds obesity drugs modestly reduce weight in adolescents, but evidence quality is low and long-term data are absent.
Review
May 14, 2026 0
Metabolic Health
CGM Devices for Longevity Tracking Lack Robust Evidence Despite Growing Hype
Continuous glucose monitors are popular in biohacking circles, but direct evidence linking CGM use to extended lifespan remains thin.
Review
May 3, 2026 0
Metabolic Health
CGMs for Longevity Seekers: Real Benefits, Real Limits and What the Evidence Actually Shows
Expert reviews of top CGM platforms reveal genuine metabolic insights — but no proof they extend lifespan in healthy adults.
Review
May 12, 2026 0
Metabolic Health
CGMs for Healthy Adults Get Expert Backing but Evidence Gaps Remain
Longevity experts endorse CGMs for metabolic optimization, but RCT evidence in non-diabetics is still thin.
Review
Apr 20, 2026 0
Metabolic Health
Insulin Resistance in Aging Is a Whole-Body Failure, Not Just a Blood Sugar Problem
A new framework redefines age-related insulin resistance as a systemic collapse of metabolic resilience spanning muscle, fat, brain, and more.
Review
May 23, 2026 0
Metabolic Health
Expert-Backed CGMs for Healthy Adults Reveal Glucose Insights With Evidence Gaps
Longevity experts endorse short CGM trials for non-diabetics, but RCT evidence remains thin. Here's what the data actually shows.
Review
Apr 22, 2026 0
Metabolic Health
CGM Devices for Longevity Biohacking Reviewed: What the Evidence Actually Shows
Six leading CGM platforms compared on accuracy, evidence quality, and longevity claims — most fall short of the hype.
Review
May 8, 2026 0
Metabolic Health
CGM Devices for Biohackers Ranked: What the Evidence Actually Shows
Expert reviews compare top CGMs for longevity use, but evidence for healthy adults remains limited. Here's what you need to know.
Review
Apr 23, 2026 0
Metabolic Health
CGMs for Longevity Biohacking: What the Experts Actually Recommend
Top longevity doctors endorse CGMs for healthy adults, but evidence is mixed. Here's what the 2026 device reviews reveal.
Review
Apr 19, 2026 0
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