20 articles
Declining Menin in the hypothalamus drives inflammation and aging. Restoring it reversed decline; D-serine amino acid improved cognition in mice.
Arginine supplements reduced toxic amyloid buildup, brain inflammation, and behavioral decline in fly and mouse Alzheimer's models.
New mouse research finds the trendy D+Q senolytic combo severely damages myelin, raising red flags for longevity self-experimenters.
Researchers identified the gene that transports queuosine, a micronutrient crucial for brain health and cancer defense, solving a decades-old mystery.
Researchers created modified psilocin that maintains antidepressant effects while dramatically reducing psychedelic side effects in mice.
UC Davis scientists created novel brain-healing molecules that activate key serotonin receptors tied to neuroplasticity — without triggering hallucinations.
Clinical trial shows solriamfetol significantly improves alertness and performance in workers who start before sunrise.
A new tool that boosts mitochondrial activity in neurons restored memory in dementia mice, suggesting energy failure drives Alzheimer's symptoms.
UK study of 165,000 dementia patients finds risperidone increases stroke risk across all groups, challenging safety assumptions.
Buck Institute finds the longevity-linked APOE2 variant shields neurons from DNA damage and cellular senescence, explaining its Alzheimer's protection.
UK study of 165,000 dementia patients finds risperidone increases stroke risk across all groups, challenging safety assumptions.
Raising Sox9 levels in aging astrocytes reduced amyloid plaque buildup and protected memory in mouse models with existing Alzheimer's symptoms.
Scientists find that TDP43 protein regulates DNA repair systems, linking neurodegeneration to cancer when repair goes wrong.
Scientists used red blood cells to transport healthy mitochondria into diseased brain cells, showing promise for Parkinson's treatment.
Stanford researchers found ribosome stalling in aging brain cells triggers faulty proteins and toxic clumps linked to Alzheimer's disease.
Cambridge researchers found a gene network that shuts off nerve repair — and an existing hormone drug that reactivates it.
A new review of 5 clinical trials finds creatine may boost mood in some women with depression, but results are inconsistent across groups.
Blocking the protein PTP1B boosted memory and cleared brain plaque in mice, with potential links to diabetes and obesity treatment.
Researchers discover toxic protein pair that kills brain cells in Alzheimer's and develop compound to block it in mice.
New gene therapy zorevunersen dramatically reduced seizures in children with severe Dravet syndrome epilepsy while improving quality of life.
