Brain Health
Spermine Acts as Molecular Glue to Clear Alzheimer's and Parkinson's Proteins
New research reveals how spermine promotes protein condensation and autophagy to combat neurodegeneration in lab models.
Research Paper
Apr 10, 2026 0
Results for "Spermidine" in Parkinson's
20 articles
Brain Health
Circadian Gene PER3 Controls Depression Through Mitochondrial NAD+ Pathway
New research reveals how the circadian clock gene PER3 regulates mood by controlling cellular energy production in the brain.
Research Paper
Apr 3, 2026 0
Brain Health
NR Supplementation Improves Brain Blood Flow and Cognition in PAD Patients
A 4-week pilot trial finds nicotinamide riboside boosts cerebrovascular response and cognitive performance in older adults with peripheral artery disease.
Research Paper
Apr 24, 2026 0
Brain Health
Psilocybin Plus NMDA Modulators Reduce Hallucinations While Boosting Brain Plasticity
Combining psilocybin with D-serine or D-cycloserine dramatically reduced hallucinogenic effects while enhancing neuroplasticity markers in mice.
Research Paper
Apr 11, 2026 0
Brain Health
PQQ Shows Promise for Alzheimer's and Parkinson's Through Multiple Brain Pathways
Review reveals how PQQ supplement protects neurons via antioxidant, mitochondrial, and anti-inflammatory mechanisms in neurodegenerative diseases.
Research Paper
Apr 4, 2026 0
Brain Health
p53-DDIT4-NF-κB Pathway Drives Depression — Curcumin Blocks It
New research maps a stress-signaling cascade linking p53 activation to brain inflammation and depression, with curcumin interrupting it.
Research Paper
May 3, 2026 0
Brain Health
Metabolic Therapy Prevents Childhood Stroke Disease in Genetic Mouse Model
Nicotinamide riboside prevents moyamoya-like brain vessel blockages by fixing cellular energy production in smooth muscle cells.
Research Paper
Apr 4, 2026 0
Brain Health
Fatty Acid Molecule Erucamide Halts Retinal Degeneration in Mice
A naturally occurring fatty acid amide activates immune cells in the retina, protecting neurons and blood vessels from degenerative damage.
Research Paper
Jun 21, 2026 0
Brain Health
Myo-Inositol Supplementation Reduces Seizures in Rare Childhood Epileptic Encephalopathy
A boy with PLCB1-related epileptic encephalopathy showed improved seizure control and stabilized brain atrophy after high-dose enteral myo-inositol supplementation.
Research Paper
Jun 23, 2026 0
Brain Health
Novel Brain Compound Shows Promise Against Alzheimer's in Mice Studies
SOMCL-668 improved memory and reduced brain damage in Alzheimer's mice by targeting sigma-1 receptors and protective pathways.
Research Paper
Mar 29, 2026 1
Brain Health
Natural Compound α-Amyrin From Colorful Fruits Protects Against Alzheimer's
AI-driven study identifies α-amyrin from fruits and vegetables as a promising Alzheimer's treatment that protects mitochondria and reduces tau tangles.
Research Paper
Mar 27, 2026 12
Brain Health
Small Molecule XL20 Extends ALS Mouse Survival by Targeting TDP-43 Toxicity
A brain-penetrant compound targets a key region of TDP-43, reducing motor neuron loss and extending survival in ALS mouse models.
Research Paper
Jul 4, 2026 0
Brain Health
Pramipexole Shows Promise for Treatment-Resistant Depression in Major UK Trial
Dopamine agonist pramipexole significantly reduced depression symptoms when added to standard antidepressants in resistant cases.
Research Paper
Apr 8, 2026 0
Brain Health
Adenosine Receptor Blocker Boosts Brain Recovery After Stroke by 40%
DPCPX treatment enhanced neurogenesis and improved motor/memory function in stroke recovery studies using advanced PET imaging.
Research Paper
Apr 9, 2026 0
Brain Health
Electromagnetic Fields Restore Brain Cell Function in Neurodegeneration Study
PEMFs repair mitochondrial damage and boost brain signaling pathways in stressed neurons, offering new therapeutic hope.
Research Paper
Apr 5, 2026 0
Brain Health
Major Rett Syndrome Treatment Study Retracted After 18 Years
Promising Cerebrolysin research for rare neurological disorder withdrawn, highlighting research integrity concerns.
Research Paper
Mar 28, 2026 2
Brain Health
Blocking a Brain Stress Protein Clears Alzheimer's Waste and Cuts Amyloid Buildup
Deleting or inhibiting astrocytic PERK restores the brain's glymphatic drainage system and dramatically reduces Aβ and tau pathology in AD mouse models.
Research Paper
May 12, 2026 0
Brain Health
New Compound Prevents Brain Degeneration in Frontotemporal Dementia Mouse Model
Researchers discover a phospholipid derivative that protects brain cells by calming overactive immune cells in dementia-prone mice.
Research Paper
Mar 29, 2026 1
Brain Health
Urolithin A Shows Neuroprotective Effects Against Brain Hemorrhage in Mice
Pomegranate metabolite urolithin A reduced brain damage and improved recovery in mouse stroke model by blocking inflammation and cell death.
Research Paper
Mar 29, 2026 2
Brain Health
New Antidepressant Strategy Targets Brain Receptors for Rapid Relief
Scientists develop pathway-selective drug that activates beneficial brain receptors while avoiding negative feedback loops.
Research Paper
Apr 8, 2026 0
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