20 articles
Scientists discover adult brain cells keep epigenetic memories from development that may fuel gliomas but also enhance regeneration.
Scientists used stem cell-derived vesicles to deliver light-activated gene therapy to the brain without surgery, reversing cognitive decline in Alzheimer's mice.
A global consortium reveals how tube type, delays, and storage temperature dramatically skew key Alzheimer's blood biomarker readings.
Scientists use brain organoids to capture individual differences in brain development, offering new insights into neurological health.
Researchers develop novel immunotherapy using modified brain cells to target Alzheimer's pathology directly in the brain.
A 6,000+ organoid study links specific cellular phenotypes to microcephaly, polymicrogyria, epilepsy, and intellectual disability with 92% classification accuracy.
OSK gene therapy targeting engram neurons restored memory to youthful levels in aged mice and Alzheimer's models, reversing senescence hallmarks.
Researchers assembled data from 200 studies to map how human brain cortex develops, revealing new insights for neurological health.
Researchers combined ultrasound with gene therapy to treat Leigh syndrome, significantly extending survival in mouse models.
DNA methylation biomarkers from a simple blood test may track cognitive aging and neurological disease risk with unprecedented precision.
New research reveals how stroke disrupts mitochondria and endoplasmic reticulum, offering targets for neuroprotection.
New single-nucleus RNA sequencing reveals immature neurons persist in aged human hippocampus and may actively support cognitive resilience in Alzheimer's disease.
Researchers modified astrocytes with chimeric antigen receptors to target amyloid plaques, showing promise for Alzheimer's treatment.
Researchers identify 25 cerebrospinal fluid proteins that better predict amyloid and tau pathology stages than current biomarkers.
Bilateral theta burst stimulation enhanced neural repair and restored function after stroke in non-human primates through multiple mechanisms.
Nicotinamide riboside prevents moyamoya-like brain vessel blockages by fixing cellular energy production in smooth muscle cells.
Researchers decode how brain cells communicate in vascular dementia, revealing potential therapeutic targets for this common form of dementia.
Microglia package healthy mitochondria into vesicles and deliver them to astrocytes, sharply reducing cognitive decline in tau-pathology mice.
New research reveals that the molecular state of immature neurons in the aged hippocampus predicts cognitive resilience — not just their number.
Scientists discover why eye movement neurons survive ALS while spinal neurons die, revealing potential therapeutic targets.
