Placental Stem Cell Secretome Tested as GvHD Treatment in Phase 3 Trial
A completed Phase 3 trial tests placental MSC secretome injections against placebo in 60 GvHD patients at an Iranian hospital.
20 articles
A completed Phase 3 trial tests placental MSC secretome injections against placebo in 60 GvHD patients at an Iranian hospital.
New cell-based treatments including CAR-T therapy could transform outcomes for systemic sclerosis patients.
HSCT therapy achieves drug-free remission in patients with treatment-resistant autoimmune conditions like lupus and rheumatoid arthritis.
Researchers modified red blood cells to teach the immune system tolerance, potentially ending need for harsh immunosuppressive drugs.
A major review in Nature Medicine explores how CAR cell therapies may achieve deep immune 'reset' in autoimmune diseases by depleting pathogenic B cells.
Chinese researchers test safer alternative to CAR-T therapy for lupus patients, achieving remission in 67% with minimal side effects.
New research reveals how a single antibody treatment creates lasting protection against autoimmune diabetes by reshaping immune cells.
Breakthrough immunotherapy approach demonstrates effectiveness in treating multiple autoimmune conditions simultaneously.
A randomized trial shows prophylactic obinutuzumab dramatically reduces steroid-requiring cGVHD after bone marrow transplant.
A major review outlines how targeted hematologic therapies are transforming outcomes in MGRS, a rare but serious cause of kidney injury.
Engineered immune cells offer new hope for treating kidney diseases that resist standard therapies, potentially improving long-term health outcomes.
Enhanced immune cells engineered with cytokines could overcome cancer's defenses and extend treatment options beyond blood cancers.
A mechanistic deep-dive into cutting-edge anti-inflammaging interventions โ from senolytic pharmacology and precision cytokine targeting to partial reprogramming strategies that aim to restore youthful immune homeostasis.
Regulatory T cells persist in brain tissue after inflammation, using CD38 to maintain immune control and prevent autoimmune relapses.
Scientists use human blood vessel organoids to decode the progression of systemic sclerosis, revealing new therapeutic targets.
Revolutionary cell therapy achieves drug-free remission in patients with severe myasthenia gravis, an autoimmune muscle disorder.
Stanford researchers used modified immune proteins to enhance neurogenesis and cognitive function in aged mouse brains.
New research reveals B cells in brain membranes play crucial roles in neural protection, aging, and neurodegenerative diseases.
Researchers identify protein stress as key factor limiting natural killer cell survival in cancer treatment.
BNT162b2 mRNA vaccine induces special immune cells that protect against severe illness and may slow aging-related decline.