iPSC-Derived Vesicles Enable Noninvasive Optogenetics to Halt Alzheimer's Progression
Scientists used stem cell-derived vesicles to deliver light-activated gene therapy to the brain without surgery, reversing cognitive decline in Alzheimer's mice.
20 articles
Scientists used stem cell-derived vesicles to deliver light-activated gene therapy to the brain without surgery, reversing cognitive decline in Alzheimer's mice.
Researchers develop novel immunotherapy using modified brain cells to target Alzheimer's pathology directly in the brain.
Researchers turned ordinary brain cells into plaque-clearing machines, reducing Alzheimer's amyloid by half in mice with one treatment.
Researchers combined ultrasound with gene therapy to treat Leigh syndrome, significantly extending survival in mouse models.
Cambridge researchers found a gene network that shuts off nerve repair โ and an existing hormone drug that reactivates it.
Scientists used red blood cells to transport healthy mitochondria into diseased brain cells, showing promise for Parkinson's treatment.
UCSF scientist reveals how engineered T-cells and CRISPR are transforming cancer treatment and prevention strategies.
Bilateral theta burst stimulation enhanced neural repair and restored function after stroke in non-human primates through multiple mechanisms.
OSK gene therapy targeting engram neurons restored memory to youthful levels in aged mice and Alzheimer's models, reversing senescence hallmarks.
PEMFs repair mitochondrial damage and boost brain signaling pathways in stressed neurons, offering new therapeutic hope.
Researchers modified astrocytes with chimeric antigen receptors to target amyloid plaques, showing promise for Alzheimer's treatment.
Italian researchers developed a biosensor to track extracellular vesicles in blood, potentially personalizing stroke rehabilitation.
Stanford researcher reveals how proteins in young blood can rejuvenate aging brains and improve cognition.
Advanced neuroimaging shows how deep brain stimulation affects neural circuits, opening doors to more precise treatments.
Duke researchers restored healthy mitochondria to damaged nerve cells, cutting pain-related behaviors by 50% in mice with nerve pain.
Nicotinamide riboside prevents moyamoya-like brain vessel blockages by fixing cellular energy production in smooth muscle cells.
Scientists use brain organoids to capture individual differences in brain development, offering new insights into neurological health.
Scientists discover adult brain cells keep epigenetic memories from development that may fuel gliomas but also enhance regeneration.
Researchers decode how brain cells communicate in vascular dementia, revealing potential therapeutic targets for this common form of dementia.
New peptide delivery system restores brain connections and memory function in Alzheimer's models, offering hope for treating cognitive decline.