iPSC-Derived Vesicles Enable Noninvasive Optogenetics to Halt Alzheimer's Progression
Scientists used stem cell-derived vesicles to deliver light-activated gene therapy to the brain without surgery, reversing cognitive decline in Alzheimer's mice.
20 articles
Scientists used stem cell-derived vesicles to deliver light-activated gene therapy to the brain without surgery, reversing cognitive decline in Alzheimer's mice.
Researchers develop novel immunotherapy using modified brain cells to target Alzheimer's pathology directly in the brain.
Researchers combined ultrasound with gene therapy to treat Leigh syndrome, significantly extending survival in mouse models.
Bilateral theta burst stimulation enhanced neural repair and restored function after stroke in non-human primates through multiple mechanisms.
OSK gene therapy targeting engram neurons restored memory to youthful levels in aged mice and Alzheimer's models, reversing senescence hallmarks.
PEMFs repair mitochondrial damage and boost brain signaling pathways in stressed neurons, offering new therapeutic hope.
Researchers modified astrocytes with chimeric antigen receptors to target amyloid plaques, showing promise for Alzheimer's treatment.
Advanced neuroimaging shows how deep brain stimulation affects neural circuits, opening doors to more precise treatments.
Nicotinamide riboside prevents moyamoya-like brain vessel blockages by fixing cellular energy production in smooth muscle cells.
Scientists use brain organoids to capture individual differences in brain development, offering new insights into neurological health.
Scientists discover adult brain cells keep epigenetic memories from development that may fuel gliomas but also enhance regeneration.
Researchers decode how brain cells communicate in vascular dementia, revealing potential therapeutic targets for this common form of dementia.
New peptide delivery system restores brain connections and memory function in Alzheimer's models, offering hope for treating cognitive decline.
New research reveals how electroacupuncture helps stroke recovery by promoting transfer of healthy mitochondria from support cells to damaged neurons.
Non-invasive brain stimulation techniques like TMS are helping stroke survivors recover language abilities by targeting specific brain regions.
New review reveals promising tau-targeting therapies showing cognitive benefits and slowed brain pathology in Alzheimer's trials.
Breakthrough study shows complete reversal of severe Alzheimer's symptoms in mice, identifying new therapeutic targets for human treatment.
Simple compound successfully treats life-threatening COQ2 deficiency in newborn, offering hope for rare mitochondrial disorders.
New research in Cell maps the fronto-insular circuits behind accelerated TMS, potentially transforming rapid depression treatment.
New brain organoid study shows autophagy-boosting compounds can clear harmful tau proteins and rescue synapses in Alzheimer's disease models.