20 articles
New research reveals FGF21 has a physiological role in reducing ER stress by amplifying the unfolded protein response through sulfide signaling.
A new ESRRA-ATG5 axis links mitochondrial recycling to arginine metabolism, and a plant polyphenol activates it to protect diabetic kidneys.
Scientists discover how FGF21 fights liver disease through a key protein, opening new treatment paths for metabolic dysfunction.
New research reveals how maltol, a widely used food flavoring, may weaken bones in diabetic patients by disrupting bone remodeling.
Daily anthocyanin supplementation helped over half of prediabetic participants return to normal glucose tolerance in just 12 weeks.
A steroid hormone activates receptor GPR56 to block ferroptosis, a form of iron-driven cell death linked to liver disease.
Blocking mTOR forces cancer cells to rewire cholesterol uptake and transport, revealing new drug targets when combined with rapamycin.
New study reveals how the diabetes drug dapagliflozin dramatically alters fat metabolism and kidney function through previously unknown pathways.
Ketone body ฮฒ-OHB prevents sepsis-induced liver damage by modifying antioxidant enzyme SOD2, offering new therapeutic approach.
Diabetes drugs like empagliflozin show surprising anti-aging effects โ mimicking caloric restriction and reducing senescent cell burden.
Two bacterial proteins that sense sulfur compounds unexpectedly regulate nitrate removal, revealing new targets for optimizing wastewater treatment.
Sodium propionate reduced liver inflammation and fat accumulation in diabetic mice fed high-fat, AGE-rich diets through multiple protective mechanisms.
Transcriptomic analysis of Pseudomonas nitroreducens TX1 identifies 241 differentially expressed genes during surfactant degradation.
Breakthrough study reveals sepiapterin dramatically outperforms existing PKU therapy, offering hope for better metabolic control.
Simple sugar supplement dramatically improved diabetes symptoms in mice by stopping inflammatory cells from releasing disease-causing particles.
New research shows FGF21 hormone prevents hypertension by activating protective cardiovascular pathways in mouse models.
Research reveals how the steroid hormone pregnenolone allows cancer cells to evade immune detection and reduces immunotherapy effectiveness.
New research shows dietary methionine enhances kidney function to clear harmful inflammatory molecules from the bloodstream.
Scientists identify IL-11 as a molecular brake on beige fat thermogenesis, and show blocking it improves metabolism in obese mice.
A newly identified mechanism shows how omega-3 fatty acids protect aging kidneys โ and why low FFAR4 receptor expression accelerates kidney disease.
