20 articles
Explore the molecular mechanisms of cellular senescence and how p16/p21 pathways drive SASP production, plus cutting-edge senolytic drug targets.
New review reveals how plant-based compounds and stem cell therapies could eliminate aging cells and restore youthful function.
Breakthrough gene editing technique dramatically increases plant protein production, potentially revolutionizing crop nutrition.
Scientists discover how tumors use glucose to survive lysosome-blocking drugs, revealing promising combination therapies.
Breakthrough organoid research reveals how to grow healthy pancreatic cells, opening new paths for cancer prevention and metabolic health.
Single-cell sequencing reveals ferroptosis drives pulpitis; thymosin ฮฑ1 restores GPX4, cuts iron overload, and reduces inflammation in cells and rats.
ProcyanidinC1, a natural senolytic, selectively eliminates senescent cells in diabetic skin, dramatically improving wound healing in mouse models.
A senolytic pairing of dasatinib and quercetin cleared senescent cells at the tendon-bone junction, dramatically improving repair strength in aged rats.
Radiation triggers a Caยฒโบ-NFATc1-Fis1 cascade that fragments mitochondria in bone marrow stem cells, halting bone repair โ and silencing Fis1 reverses it.
Researchers identified why some fat cancers become aggressive and found a potential new therapy approach using existing drugs.
New research reveals how a key protein's behavior changes during intestinal cell development, offering insights into tissue regeneration.
Novel nanogel therapy targets mitochondrial ROS to break the inflammation-hypoxia cycle in periodontitis, showing strong preclinical results.
Blocking zinc transport in stem cell-derived pancreatic islets improves their survival and function after transplantation for diabetes treatment.
Discover how revolutionary drugs target 'zombie cells' that accumulate with age, potentially reversing aging and extending healthspan.
Early data suggests the latest KRAS-targeting drugs outperform their predecessors in lung cancer treatment, marking a potential breakthrough.
A phase 2b trial finds allogeneic MSC infusions improved 6-minute walk distance by 63 meters vs placebo at 9 months in frail older adults.
The latest cancer therapies unveiled at ASCO 2026 signal major shifts in how oncologists detect, treat, and manage cancer long-term.
A landmark Cell study reveals p53 actively enables chemical reprogramming to pluripotency, overturning assumptions and boosting regenerative medicine safety.
Scientists discover how plant compounds enhance stem cell therapy for kidney disease through improved cellular messaging.
Researchers discovered how GAS6 protein rejuvenates aged stem cells, potentially revolutionizing diabetic wound treatment and anti-aging medicine.
