Beyond Folic Acid: Restoring Sulfur Metabolism to Combat Hyperhomocysteinemia
A comprehensive review reveals how transsulfuration pathway products and HโS-donors may offer new therapeutic avenues for hyperhomocysteinemia.
27 articles
A comprehensive review reveals how transsulfuration pathway products and HโS-donors may offer new therapeutic avenues for hyperhomocysteinemia.
A novel mass spectrometry method maps 482,000 protein-metabolite relationships, revealing how LRRC58 governs cysteine catabolism and hepatic cholesterol.
New research shows taurine suppresses p53-driven senescence in pancreatic ฮฒ-cells, offering a potential strategy to preserve insulin secretion with age.
A bile acid found in blood predicts and treats obesity-induced endothelial dysfunction through a newly discovered FXR-ATF4 metabolic axis.
A taurine transporter epigenetically upregulated by arsenic drives malignant skin cell transformation but simultaneously sensitizes cancer cells to copper-induced death.
Tiny ocean chemicals called copepodamides trigger dramatic defenses in plankton, reshaping food webs and driving harmful algal blooms.
Scientists discover that taurine-based tRNA modifications protect cardiomyocytes from ferroptotic cell death, opening new avenues for heart attack therapy.
A multi-omics study reveals how disrupted taurine metabolism reshapes the bladder cancer tumor microenvironment, fueling immune evasion and anti-PD-1 resistance.
Tumor environments trigger cellular stress that shuts down immune responses, but targeting these pathways may enhance immunotherapy effectiveness.
New research reveals how taurine dioxygenase evolved across species and identifies unique genetic signatures that distinguish it from related enzymes.
New research challenges the idea that falling taurine levels drive aging, finding levels actually increase or stay stable with age.
Scientists used AI to identify gut microbiome signatures that predict digestive cancers and IBD before symptoms appear.