20 articles
New research shows dietary methionine enhances kidney function to clear harmful inflammatory molecules from the bloodstream.
A newly identified protein shields the liver from alcohol injury by bridging mitochondria and fat droplets to enhance fatty acid oxidation.
A new ESRRA-ATG5 axis links mitochondrial recycling to arginine metabolism, and a plant polyphenol activates it to protect diabetic kidneys.
Breakthrough study reveals sepiapterin dramatically outperforms existing PKU therapy, offering hope for better metabolic control.
New research shows phosphatidylserine supplementation reduces liver fat and inflammation while improving glucose control through enhanced fat metabolism.
Ketone body ฮฒ-OHB prevents sepsis-induced liver damage by modifying antioxidant enzyme SOD2, offering new therapeutic approach.
Daily anthocyanin supplementation helped over half of prediabetic participants return to normal glucose tolerance in just 12 weeks.
A new review links feline age-related obesity to SASP-driven chronic inflammation, offering translational insights for human metabolic disease.
NIH study identifies metabolic mechanism behind controversial skin condition and demonstrates successful treatment with mitochondrial complex I inhibitors.
Weekly tirzepatide injections led to up to 22% weight loss in Japanese participants, with 96-100% achieving clinically significant results.
A 2025 mini-review synthesizes RCTs and meta-analyses showing hypertonic dextrose prolotherapy rivals or beats standard OA injections.
A landmark JCI review maps the expanding pharmacological arsenal for MASH, from GLP-1 agonists to triple receptor therapies and precision medicine.
New research reveals pulsed electromagnetic field therapy selectively enhances ATP-linked mitochondrial respiration, pointing to a specific cellular energy mechanism.
Veterinary sedative medetomidine increasingly adulterates street fentanyl, causing severe cardiac effects and heightened overdose risk.
Sodium propionate reduced liver inflammation and fat accumulation in diabetic mice fed high-fat, AGE-rich diets through multiple protective mechanisms.
A newly identified mechanism shows how omega-3 fatty acids protect aging kidneys โ and why low FFAR4 receptor expression accelerates kidney disease.
A real-world study of 15,000+ patients finds tirzepatide outperforms both semaglutide and liraglutide in preventing major cardiac events.
Mice lacking the HDAC9 gene gained less fat with age, accumulated fewer senescent cells, and showed improved mitochondrial respiration in adipose tissue.
A systematic review of 8 studies finds tirzepatide significantly reduces hsCRP and IL-6 across all doses and populations.
Combining cold exposure with exercise activates a key metabolic pathway to reduce liver fat and fibrosis more effectively than either intervention alone.
