Results for "Telomerase Activation" in Cancer

20 articles

Telomerase Vaccine Plus Checkpoint Blockade Targets HPV-Driven Cancers
Cancer Research

Telomerase Vaccine Plus Checkpoint Blockade Targets HPV-Driven Cancers

A completed Phase 2 trial tests UCPVax cancer vaccine combined with atezolizumab in cervical, anal, and head-and-neck cancers.

Clinical Trial
May 10, 2026 0
Liquid Biopsy for Sarcoma: Can cfDNA and Telomere Mutations Predict Recurrence
Cancer Research

Liquid Biopsy for Sarcoma: Can cfDNA and Telomere Mutations Predict Recurrence

Researchers explored whether cancer-derived cell-free DNA and telomere maintenance mutations could serve as early warning biomarkers in soft tissue sarcoma patients.

Clinical Trial
May 16, 2026 0
HDAC Inhibitor Plus Checkpoint Blocker Tested in Advanced Lung Cancer Trial
Cancer Research

HDAC Inhibitor Plus Checkpoint Blocker Tested in Advanced Lung Cancer Trial

A phase 1/2 trial combined mocetinostat and durvalumab in 83 patients with advanced solid tumors and NSCLC.

Clinical Trial
May 7, 2026 0
Engineered Immune Cells Show Promise Against Advanced Cancer in Early Trial
Cancer Research

Engineered Immune Cells Show Promise Against Advanced Cancer in Early Trial

Scientists modified patients' immune cells to better recognize and attack cancer tumors expressing NY-ESO-1 protein.

Clinical Trial
Mar 28, 2026 0
T-VEC Plus Pembrolizumab Tested in Melanoma After Anti-PD-1 Failure
Cancer Research

T-VEC Plus Pembrolizumab Tested in Melanoma After Anti-PD-1 Failure

Phase 2 trial explores whether combining oncolytic virus therapy with immunotherapy can rescue patients whose melanoma progressed on PD-1 blockade.

Clinical Trial
May 29, 2026 0
CD226 Immune Receptor Explored as Predictor of Immunotherapy Response in Advanced Liver Cancer
Cancer Research

CD226 Immune Receptor Explored as Predictor of Immunotherapy Response in Advanced Liver Cancer

A French trial investigated whether circulating immune cell profiles, specifically CD226 expression, could predict who responds to Atezolizumab/Bevacizumab in advanced HCC.

Clinical Trial
Jun 9, 2026 0
CAR-T Cell Therapy Shows Promise Against Advanced Liver Cancer in Early Trial
Cancer Research

CAR-T Cell Therapy Shows Promise Against Advanced Liver Cancer in Early Trial

Engineered immune cells target liver cancer protein in phase I safety study, though trial ended early with 10 patients.

Clinical Trial
Mar 29, 2026 1
Enhanced CAR-T Cell Therapy Shows Promise Against Treatment-Resistant Blood Cancers
Cancer Research

Enhanced CAR-T Cell Therapy Shows Promise Against Treatment-Resistant Blood Cancers

Modified immune cells engineered to overcome cancer's defenses completed safety testing in lymphoma patients.

Clinical Trial
Mar 29, 2026 12
Amgen's PSMA Bispecific T-Cell Engager Acapatamab Tested in Advanced Prostate Cancer
Cancer Research

Amgen's PSMA Bispecific T-Cell Engager Acapatamab Tested in Advanced Prostate Cancer

Phase 1 trial of acapatamab, a PSMA-targeting bispecific T-cell engager, enrolls 212 men with metastatic castration-resistant prostate cancer.

Clinical Trial
May 13, 2026 0
Engineered T Cells Show Promise Against Deadly Mesothelioma Cancer
Cancer Research

Engineered T Cells Show Promise Against Deadly Mesothelioma Cancer

Small trial tests modified immune cells injected directly into chest cavity to fight aggressive cancer with 12-month survival rate.

Clinical Trial
Mar 28, 2026 1
Oncolytic Virus Therapy Shows Promise Against Advanced Metastatic Cancers
Cancer Research

Oncolytic Virus Therapy Shows Promise Against Advanced Metastatic Cancers

New viral therapy ASP9801 targets solid tumors directly, potentially offering hope for patients with advanced metastatic cancer.

Clinical Trial
Mar 28, 2026 0
Triple Immune Checkpoint Blockade Tested in Advanced Solid Tumors
Cancer Research

Triple Immune Checkpoint Blockade Tested in Advanced Solid Tumors

A Phase 1/2 trial explores combining KIR, PD-1, and CTLA-4 inhibitors to unlock stronger anti-tumor immunity.

Clinical Trial
May 20, 2026 0
Cancer Trial Tests Novel Immune Booster BAY 2416964 With Pembrolizumab
Cancer Research

Cancer Trial Tests Novel Immune Booster BAY 2416964 With Pembrolizumab

Researchers tested a new drug combination targeting immune suppression in advanced solid tumors before early termination.

Clinical Trial
Mar 28, 2026 0
Strength Training Fights Inflammaging in Bone Marrow Transplant Survivors
Cancer Research

Strength Training Fights Inflammaging in Bone Marrow Transplant Survivors

A 10-week supervised strength program targets chronic inflammation and self-efficacy in long-term allogeneic HCT survivors.

Clinical Trial
May 25, 2026 0
Modified T Cells Show Promise Against Childhood Blood Cancers in NCI Trial
Cancer Research

Modified T Cells Show Promise Against Childhood Blood Cancers in NCI Trial

Researchers modified children's own immune cells to fight B-cell leukemia and lymphoma when standard treatments failed.

Clinical Trial
Mar 28, 2026 0
CAR-T Cell Therapy Shows Promise Against Treatment-Resistant Multiple Myeloma
Cancer Research

CAR-T Cell Therapy Shows Promise Against Treatment-Resistant Multiple Myeloma

Genetically modified immune cells target blood cancer that stopped responding to standard treatments in 28-patient trial.

Clinical Trial
Mar 28, 2026 0
Melanoma Drug Resistance Linked to Cellular Communication Vesicles Called Exosomes
Cancer Research

Melanoma Drug Resistance Linked to Cellular Communication Vesicles Called Exosomes

French researchers studied how tiny cellular packages called exosomes may help melanoma cells resist treatment and spread throughout the body.

Clinical Trial
Mar 28, 2026 0
PULSAR Radiation Plus IMSA101 Immunotherapy Trial in Oligoprogressive Cancers Terminated Early
Cancer Research

PULSAR Radiation Plus IMSA101 Immunotherapy Trial in Oligoprogressive Cancers Terminated Early

A Phase 2 trial combining adaptive stereotactic radiotherapy with IMSA101 and checkpoint inhibitors was halted after enrolling only 16 patients.

Clinical Trial
May 14, 2026 0
Natural Killer Cell Therapy Shows Promise for Advanced Cancer Treatment
Cancer Research

Natural Killer Cell Therapy Shows Promise for Advanced Cancer Treatment

Autologous NK cell therapy combined with immunotherapy tested in 27 patients with treatment-resistant cancers.

Clinical Trial
Mar 29, 2026 0
Turin Study Maps Why Multiple Myeloma Escapes Anti-CD38 Immunotherapy
Cancer Research

Turin Study Maps Why Multiple Myeloma Escapes Anti-CD38 Immunotherapy

Italian researchers track genomic and cellular changes in myeloma patients to uncover why anti-CD38 treatments stop working.

Clinical Trial
Jun 16, 2026 0
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