Metabolic Health
SGLT2 Inhibitors May Slow Aging by Clearing Senescent Cells
Diabetes drugs like empagliflozin show surprising anti-aging effects — mimicking caloric restriction and reducing senescent cell burden.
Research Paper
May 15, 2026 0
Results for "Telomere Interventions" in Diabetes
20 articles
Metabolic Health
AI-Powered Nutrigenetics Slashes BMI and Reverses Biological Aging in Morbid Obesity
A 6-month AI-driven personalized diet intervention cut BMI by 33% and reduced biological age by 8 years in morbidly obese patients.
Research Paper
May 21, 2026 0
Metabolic Health
Deleting HDAC9 Gene Slows Fat Tissue Aging and Boosts Mitochondrial Function in Mice
Mice lacking the HDAC9 gene gained less fat with age, accumulated fewer senescent cells, and showed improved mitochondrial respiration in adipose tissue.
Research Paper
Apr 27, 2026 0
Metabolic Health
Scientists Map How Cholesterol Controls Cell Growth Through mTOR Pathway
New cryo-EM structures reveal how LYCHOS protein senses cholesterol levels to regulate mTORC1 signaling, offering drug targets for aging.
Research Paper
Apr 5, 2026 0
Metabolic Health
mTOR Inhibition Triggers Hidden Lipid Survival Pathways That Fuel Cancer Growth
Blocking mTOR forces cancer cells to rewire cholesterol uptake and transport, revealing new drug targets when combined with rapamycin.
Research Paper
May 22, 2026 0
Metabolic Health
Exercise Prevents Chronic Disease Through Direct Biological Mechanisms
New research reveals how regular physical activity directly prevents and slows progression of major age-related diseases.
Research Paper
Mar 28, 2026 1
Metabolic Health
GLP-1 Receptor Agonists Show Promise for Longevity and Metabolic Health
New England Journal review explores the expanding therapeutic potential of GLP-1 drugs beyond diabetes treatment.
Research Paper
Apr 9, 2026 0
Metabolic Health
New Immune Engineering Approach Shows Promise for Diabetes Islet Transplants
Researchers explore targeted immune strategies to improve pancreatic islet transplant success rates for diabetes treatment.
Research Paper
Mar 28, 2026 0
Metabolic Health
New Local Immune Engineering Approach Could Transform Diabetes Islet Transplants
Researchers shift from systemic B-cell targeting to localized immune control, potentially improving transplant success rates.
Research Paper
Mar 28, 2026 0
Metabolic Health
Aging and Western Diet Team Up to Sabotage Liver Thyroid Hormone Signaling
A mouse study reveals how aging and poor diet synergistically disrupt liver thyroid hormone metabolism, accelerating fatty liver disease — and why resmetirom may help.
Research Paper
Jun 24, 2026 0
Metabolic Health
Mitochondrial Energy Production Controls Immune Cell Cancer-Fighting Ability
New research reveals how mitochondrial metabolism regulates dendritic cells' ability to activate anti-tumor immunity.
Research Paper
Apr 17, 2026 0
Metabolic Health
DunedinPACE Epigenetic Clock Predicts Metabolic Syndrome 7 Years Before Onset
New study shows DunedinPACE aging biomarker can predict who will develop metabolic syndrome years in advance, outperforming other epigenetic clocks.
Research Paper
Apr 2, 2026 0
Metabolic Health
Topical Steroid Withdrawal Linked to Mitochondrial NAD+ Excess, Treatable with Metformin
NIH study identifies metabolic mechanism behind controversial skin condition and demonstrates successful treatment with mitochondrial complex I inhibitors.
Research Paper
Apr 4, 2026 0
Metabolic Health
PEMF Therapy Boosts Mitochondrial ATP Synthesis Without Affecting Uncoupled Respiration
New research reveals pulsed electromagnetic field therapy selectively enhances ATP-linked mitochondrial respiration, pointing to a specific cellular energy mechanism.
Research Paper
Apr 22, 2026 0
Metabolic Health
Precision Obesity Medicine Maps Best Drugs to Patient Phenotype and Age
A comprehensive 2025 review framework matches GLP-1 agonists, tirzepatide, and other AOMs to specific obesity phenotypes, complications, and life stages.
Research Paper
Jun 22, 2026 0
Metabolic Health
New Injectable Drug Cuts Cholesterol 28% in Teens With Genetic High Cholesterol
Inclisiran safely reduced LDL cholesterol by 28% in adolescents with familial hypercholesterolemia, offering hope for early intervention.
Research Paper
Mar 29, 2026 0
Metabolic Health
MASH Treatment Revolution: Semaglutide, Tirzepatide Lead a New Drug Era
A landmark JCI review maps the expanding pharmacological arsenal for MASH, from GLP-1 agonists to triple receptor therapies and precision medicine.
Research Paper
May 30, 2026 0
Metabolic Health
Metabolic Syndrome Accelerates Biological Aging by Over a Year
Large NHANES study reveals metabolic syndrome causes measurable acceleration in epigenetic aging clocks, offering new targets for intervention.
Research Paper
Apr 3, 2026 0
Metabolic Health
Shorter Romosozumab Treatment Shows Promise for Bone Health in New Clinical Approach
Three-month romosozumab protocol offers pragmatic solution for osteoporosis treatment with potentially improved patient outcomes.
Research Paper
Mar 29, 2026 0
Metabolic Health
Inclisiran Shows Promise for Treating High Cholesterol in Children
New research examines whether the cholesterol-lowering drug inclisiran could benefit pediatric patients with genetic high cholesterol.
Research Paper
Mar 29, 2026 0
Page 1 of 2Next