20 articles
Researchers shift from systemic B-cell targeting to localized immune control, potentially improving transplant success rates.
Researchers explore targeted immune strategies to improve pancreatic islet transplant success rates for diabetes treatment.
New research reveals how blood vessel maturity around transplanted insulin-producing cells determines long-term survival.
New research reveals how mitochondrial metabolism regulates dendritic cells' ability to activate anti-tumor immunity.
Scientists identify how different immune cells use specific nutrient transporters, revealing new targets for autoimmune diseases.
Mice lacking the HDAC9 gene gained less fat with age, accumulated fewer senescent cells, and showed improved mitochondrial respiration in adipose tissue.
Brief weekly PEMF exposures increased quail embryo weight by ~20%, body length by ~15%, and upregulated key oxidative muscle genes.
Explore how brown and beige fat activity declines with age, the metabolic ripple effects this creates, and the evidence-backed lifestyle strategies that can help restore thermogenic function.
New research reveals how immune cell dysfunction, particularly T-cell exhaustion, contributes to metabolic syndrome in different fat deposits.
Meta-analysis reveals patients regain substantial weight after discontinuing semaglutide, tirzepatide, and liraglutide therapy.
New research shows dietary methionine enhances kidney function to clear harmful inflammatory molecules from the bloodstream.
A completed trial investigates whether replenishing glutathione precursors can reverse metabolic dysfunction in elderly adults.
New study reveals how endurance exercise transforms fat-burning brown adipose tissue in just six weeks of training.
New research reveals how glucose metabolism directly controls fat tissue expansion through a novel epigenetic pathway involving JMJD1A.
A completed OSU trial investigates whether short-term exercise training can restore impaired mitochondrial cleanup pathways in overweight and obese skeletal muscle.
A large real-world study finds post-transplant diabetes requiring insulin marks a high-risk metabolic phenotype with far worse graft and patient outcomes.
Three new NIH-funded findings tackle metabolic aging, cardiovascular risk, and a surprising hormonal brake on brain tumors.
A 10-year MRI follow-up of two RCTs finds visceral fat reduction — not weight loss — drives lasting cardiometabolic protection.
New research reveals how specific gene combinations affect how quickly pre-diabetes advances to full type 1 diabetes.
Deep dive into uncoupling protein 1 mechanisms, sympathetic nervous system control, and therapeutic strategies for metabolic health and longevity.
