20 articles
Researchers shift from systemic B-cell targeting to localized immune control, potentially improving transplant success rates.
Researchers explore targeted immune strategies to improve pancreatic islet transplant success rates for diabetes treatment.
New research reveals how blood vessel maturity around transplanted insulin-producing cells determines long-term survival.
New research reveals how mitochondrial metabolism regulates dendritic cells' ability to activate anti-tumor immunity.
Scientists identify how different immune cells use specific nutrient transporters, revealing new targets for autoimmune diseases.
Mice lacking the HDAC9 gene gained less fat with age, accumulated fewer senescent cells, and showed improved mitochondrial respiration in adipose tissue.
Brief weekly PEMF exposures increased quail embryo weight by ~20%, body length by ~15%, and upregulated key oxidative muscle genes.
New research reveals how immune cell dysfunction, particularly T-cell exhaustion, contributes to metabolic syndrome in different fat deposits.
Meta-analysis reveals patients regain substantial weight after discontinuing semaglutide, tirzepatide, and liraglutide therapy.
New research shows dietary methionine enhances kidney function to clear harmful inflammatory molecules from the bloodstream.
New research reveals how glucose metabolism directly controls fat tissue expansion through a novel epigenetic pathway involving JMJD1A.
A large real-world study finds post-transplant diabetes requiring insulin marks a high-risk metabolic phenotype with far worse graft and patient outcomes.
A 10-year MRI follow-up of two RCTs finds visceral fat reduction — not weight loss — drives lasting cardiometabolic protection.
New research reveals how specific gene combinations affect how quickly pre-diabetes advances to full type 1 diabetes.
Scientists discover signaling pathways that could enhance insulin-producing cells and improve diabetes treatment outcomes.
New cryo-EM structures reveal how LYCHOS protein senses cholesterol levels to regulate mTORC1 signaling, offering drug targets for aging.
Research reveals how the steroid hormone pregnenolone allows cancer cells to evade immune detection and reduces immunotherapy effectiveness.
A newly discovered lipid recycling loop driven by DGAT enzymes generates significant body heat — and it's been hiding in plain sight.
A dual-action therapy combining a glucose-responsive hydrogel with stem cell exosomes dramatically speeds diabetic wound closure in mice.
A new ESRRA-ATG5 axis links mitochondrial recycling to arginine metabolism, and a plant polyphenol activates it to protect diabetic kidneys.
