Newborn Hearts Use Immune System to Regenerate After Injury
Scientists discover how complement proteins help baby hearts heal completely, offering clues for adult cardiac repair.
20 articles
Scientists discover how complement proteins help baby hearts heal completely, offering clues for adult cardiac repair.
A 330-patient multicenter RCT tests whether thymosin ฮฑ1 can curb immune dysregulation and organ dysfunction after acute type A aortic dissection repair.
Researchers propose targeting lymph node entry mechanisms to improve immune tolerance in cardiac transplant recipients, potentially reducing rejection.
Small trial tests safety of injecting patients' own cardiac stem cells to regrow dead heart tissue and restore function.
Scientists discover how damaged heart cells transform into new blood vessels, potentially revolutionizing heart failure treatment.
A specific CD40 signaling branch boosts macrophage cleanup of dead cells after MI, improving cardiac recovery in mice.
Researchers created synthetic immune receptors that boost macrophages' ability to clear cellular debris, reducing inflammation in liver and heart disease.
Researchers tested whether stem cells from healthy hearts could help repair damage in heart attack patients, offering hope for cardiac regeneration.
Researchers tested injecting cardiac stem cells directly into heart arteries after heart attacks to promote healing and regeneration.
A feedforward ANGPT-TIE2 signaling loop amplifies PIK3CA-driven venous malformations, pointing to TIE2 inhibition as a more effective therapy than mTOR blockade.
A distinct immune remodeling process โ separate from classical immunosenescence โ predicts arterial stiffness with surprising accuracy.
Scientists discover how to enhance cancer immunotherapy by converting tumor-supporting immune cells into tumor-fighting ones.
Breakthrough study shows one epigenetic factor can transform cardiac fibroblasts into heart muscle cells, improving function after myocardial infarction.
Researchers discovered specific cell markers that predict which leukemia patients will achieve lasting remission from CAR-T therapy.
Inefficient cellular cleanup in the heart creates inflammation that damages non-regenerative heart muscle cells.
Researchers tested a novel stem cell therapy using umbilical cord cells on a pericardial matrix to repair heart tissue after heart attacks.
A single cardiovascular event creates inflammatory memory that drives chronic disease across multiple organs for years.
A muscle enzyme that declines in heart attack patients may hold the key to preserving cardiac function after MI.
Natural isoflavone prevents cardiac enlargement through novel mitochondrial protection pathway, offering new therapeutic approach.
Deleting GTPBP3 in endothelial cells blocks angiogenesis via mtROS overload โ and a mitochondria-targeted antioxidant reverses the damage.