20 articles
New research reveals that gene therapy for SMA causes significant immune activation, suggesting immune dysfunction is central to the disease.
Scientists discover adult brain cells keep epigenetic memories from development that may fuel gliomas but also enhance regeneration.
New research reveals the brain actively directs development of its surrounding lymphatic immune network via specialized glial cells and neural signals.
Scientists decode how zebrafish regrow damaged brain tissue, offering new pathways for treating human neurological diseases.
New research reveals how immune cytokines IL-4 and IL-13 directly signal to brain neurons to regulate synapses and cognitive function.
Blocking brain lymphatic drainage triggers age-dependent compensatory responses — young rats adapt, middle-aged rats largely cannot, with proteomic signs of neurodegeneration in both.
OSK gene therapy targeting engram neurons restored memory to youthful levels in aged mice and Alzheimer's models, reversing senescence hallmarks.
Scientists discover how brain neurons regulate acute lung injury by controlling immune cell activity through the nervous system.
IRISeq maps gene expression across aging mouse brains, finding lymphocytes fuel neuroinflammation and accelerate cellular aging.
Bilateral theta burst stimulation enhanced neural repair and restored function after stroke in non-human primates through multiple mechanisms.
Scientists discover three distinct immune cell types guarding the brain's choroid plexus, opening new therapeutic pathways.
Researchers develop novel immunotherapy using modified brain cells to target Alzheimer's pathology directly in the brain.
Microglia package healthy mitochondria into vesicles and deliver them to astrocytes, sharply reducing cognitive decline in tau-pathology mice.
New research reveals how TSC2 mutations suppress translation of autism and epilepsy genes, offering potential therapeutic targets.
New research reveals how glucose availability directs brain cell proliferation via a metabolic-epigenetic axis, with implications for MS and brain repair.
New research reveals that the molecular state of immature neurons in the aged hippocampus predicts cognitive resilience — not just their number.
Scientists uncover the molecular mechanisms driving microglial aging in the brain, offering insights into neurodegeneration.
A specific cholinergic brain circuit drives post-surgery memory decline in aging — and reactivating it rescues both cognition and neurogenesis.
Scientists use brain organoids to capture individual differences in brain development, offering new insights into neurological health.
New research reveals dendrite branching is driven by random growth, with ligand contacts acting as brakes to sculpt precise neural architecture.
