Your Thymus Can Repair Itself โ Here's How That Could Transform Immune Aging
A landmark review reveals the molecular pathways driving thymic self-repair after injury, with major implications for aging immunity.
20 articles
A landmark review reveals the molecular pathways driving thymic self-repair after injury, with major implications for aging immunity.
Scientists built a microwell-based mini-thymus that replicates native thymic biology and supports T cell development at scale.
Harvard researchers identify a rare mesenchymal cell type that regenerates the thymus and boosts T cell immunity in aged animals.
Kyoto researchers built the first fully in vitro system that guides stem cells through every stage of human thymus development, producing functional T cells.
A newly discovered immune pathway suppresses thymic regeneration post-damage โ and blocking IL-18 may restore it.
Researchers found a way to restore aging stem cells' healing power, potentially improving treatments for immune diseases.
Researchers identified key cellular switches that enable newborn hearts to regenerate, revealing potential targets for adult cardiac repair.
Researchers identify methods to induce powerful regenerative cell clusters in mammals using temporary pluripotency factors.
New research reveals how thrombopoietin hormone establishes lifelong blood stem cell hierarchy in newborns.
Researchers reprogrammed immune cells to restore tolerance and heal autoimmune hepatitis, offering hope for treating autoimmune diseases.
Scientists discover cells can recover from dying conditions through a programmed revival process that enhances wound healing and regeneration.
New review reveals how nerve signals, Schwann cells, and nerve-derived cells orchestrate tissue healing and regeneration.
Single-cell sequencing reveals ferroptosis drives pulpitis; thymosin ฮฑ1 restores GPX4, cuts iron overload, and reduces inflammation in cells and rats.
Scientists decode how axolotl digits regrow, uncovering unique mechanisms that could revolutionize regenerative medicine.
Researchers identify how host macrophages destroy foreign cells in embryos โ and three strategies to stop it, boosting organ-growing chimeras.
Injured artery smooth muscle cells temporarily become stem-like progenitors, fueling the dangerous buildup that narrows blood vessels after cardiac procedures.
The transcription factor Lhx2 in liver stellate cells promotes regeneration and suppresses fibrosis via TGF-ฮฒ and HGF pathways.
Japanese researchers develop minimally invasive method to transform T cells into glutamatergic neurons using just 5 factors.
New research reveals eosinophils protect hematopoietic stem cells, suggesting immune balance is crucial for regenerative capacity.
Researchers propose using partial reprogramming to rejuvenate donor organs outside the body before transplantation.