39 articles
Elysium Health launches Creatine+, blending creatine, HMB, and pomegranate polyphenols to support strength, recovery, and healthy aging.
A deep mechanistic examination of mitophagy's molecular circuitry — from ubiquitin chain topology to mitochondrial-nuclear crosstalk — and the emerging therapeutic strategies targeting this pathway to slow aging.
Go beyond the basics and explore the precise signaling pathways, protein machinery, and regulatory networks that determine which mitochondria live and which get recycled — and why this matters for aging.
A comprehensive review reveals mitochondrial quality control failures precede kidney damage in diabetes, spotlighting emerging drug targets.
A comprehensive 2026 review reveals how mitochondrial self-cleaning gone wrong underlies neurodegeneration, heart disease, cancer, and aging.
Small molecule AA-20 clears protein aggregates and lipid droplets, extending C. elegans lifespan through a novel mTOR-independent autophagy pathway.
Deleting HSP60 in astrocytes causes mitochondrial failure and cellular senescence, disrupting neuroregeneration via the S1P/truncated-BDNF pathway.
Go beyond probiotics and fiber — explore the cutting-edge science of fecal microbiota transplantation, engineered postbiotics, and how the gut orchestrates systemic aging through immune and neural circuits.
Go beyond antioxidant basics to explore how polyphenols hijack transcription factor networks, remodel chromatin, and what randomized trials actually show about aging biomarkers.
A comprehensive review reveals how SCFAs, bile acids, and tryptophan metabolites reshape the tumor immune microenvironment in GI cancers.
A leading aging researcher audits NMN, urolithin A, spermidine, and more — revealing what actually works and what falls short.
A quercetin, NR, urolithin A, and alpha-lipoic acid combination boosted remaining lifespan in aged mice by 33%, even on a Western diet.
